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Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies.
La Regina G, Edler MC, Brancale A, Kandil S, Coluccia A, Piscitelli F, Hamel E, De Martino G, Matesanz R, Díaz JF, Scovassi AI, Prosperi E, Lavecchia A, Novellino E, Artico M, Silvestri R. La Regina G, et al. Among authors: brancale a. J Med Chem. 2007 Jun 14;50(12):2865-74. doi: 10.1021/jm061479u. Epub 2007 May 12. J Med Chem. 2007. PMID: 17497841
Arylthioindoles, potent inhibitors of tubulin polymerization.
De Martino G, La Regina G, Coluccia A, Edler MC, Barbera MC, Brancale A, Wilcox E, Hamel E, Artico M, Silvestri R. De Martino G, et al. Among authors: brancale a. J Med Chem. 2004 Dec 2;47(25):6120-3. doi: 10.1021/jm049360d. J Med Chem. 2004. PMID: 15566282
Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
Romagnoli R, Baraldi PG, Carrion MD, Lopez Cara C, Preti D, Fruttarolo F, Pavani MG, Tabrizi MA, Tolomeo M, Grimaudo S, Di Cristina A, Balzarini J, Hadfield JA, Brancale A, Hamel E. Romagnoli R, et al. Among authors: brancale a. J Med Chem. 2007 May 3;50(9):2273-7. doi: 10.1021/jm070050f. Epub 2007 Apr 10. J Med Chem. 2007. PMID: 17419607
Synthesis and biological evaluation of 1-methyl-2-(3',4',5'-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors.
Romagnoli R, Baraldi PG, Sarkar T, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tabrizi MA, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Hsieh HP, Hamel E. Romagnoli R, et al. Among authors: brancale a. J Med Chem. 2008 Mar 13;51(5):1464-8. doi: 10.1021/jm7011547. Epub 2008 Feb 9. J Med Chem. 2008. PMID: 18260616
Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
Romagnoli R, Baraldi PG, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Sarkar T, Hamel E. Romagnoli R, et al. Among authors: brancale a. Bioorg Med Chem. 2008 May 15;16(10):5367-76. doi: 10.1016/j.bmc.2008.04.026. Epub 2008 Apr 15. Bioorg Med Chem. 2008. PMID: 18440234
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-6-substituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine derivatives as antimitotic agents and inhibitors of tubulin polymerization.
Romagnoli R, Baraldi PG, Carrion MD, Cruz-Lopez O, Cara CL, Tolomeo M, Grimaudo S, Di Cristina A, Pipitone MR, Balzarini J, Kandil S, Brancale A, Sarkar T, Hamel E. Romagnoli R, et al. Among authors: brancale a. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5041-5. doi: 10.1016/j.bmcl.2008.08.006. Epub 2008 Aug 6. Bioorg Med Chem Lett. 2008. PMID: 18725179 Free PMC article.
226 results