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Page 1
Cyclic benzamidines as orally efficacious NR2B-selective NMDA receptor antagonists.
Nguyen KT, Claiborne CF, McCauley JA, Libby BE, Claremon DA, Bednar RA, Mosser SD, Gaul SL, Connolly TM, Condra CL, Bednar B, Stump GL, Lynch JJ, Koblan KS, Liverton NJ. Nguyen KT, et al. Among authors: condra cl. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3997-4000. doi: 10.1016/j.bmcl.2007.04.084. Epub 2007 Apr 29. Bioorg Med Chem Lett. 2007. PMID: 17498948
Orally efficacious NR2B-selective NMDA receptor antagonists.
Claiborne CF, McCauley JA, Libby BE, Curtis NR, Diggle HJ, Kulagowski JJ, Michelson SR, Anderson KD, Claremon DA, Freidinger RM, Bednar RA, Mosser SD, Gaul SL, Connolly TM, Condra CL, Bednar B, Stump GL, Lynch JJ, Macaulay A, Wafford KA, Koblan KS, Liverton NJ. Claiborne CF, et al. Among authors: condra cl. Bioorg Med Chem Lett. 2003 Feb 24;13(4):697-700. doi: 10.1016/s0960-894x(02)01061-2. Bioorg Med Chem Lett. 2003. PMID: 12639561
NR2B-selective N-methyl-D-aspartate antagonists: synthesis and evaluation of 5-substituted benzimidazoles.
McCauley JA, Theberge CR, Romano JJ, Billings SB, Anderson KD, Claremon DA, Freidinger RM, Bednar RA, Mosser SD, Gaul SL, Connolly TM, Condra CL, Xia M, Cunningham ME, Bednar B, Stump GL, Lynch JJ, Macaulay A, Wafford KA, Koblan KS, Liverton NJ. McCauley JA, et al. Among authors: condra cl. J Med Chem. 2004 Apr 8;47(8):2089-96. doi: 10.1021/jm030483s. J Med Chem. 2004. PMID: 15056006
Discovery and initial structure-activity relationships of trisubstituted ureas as thrombin receptor (PAR-1) antagonists.
Barrow JC, Nantermet PG, Selnick HG, Glass KL, Ngo PL, Young MB, Pellicore JM, Breslin MJ, Hutchinson JH, Freidinger RM, Condra C, Karczewski J, Bednar RA, Gaul SL, Stern A, Gould R, Connolly TM. Barrow JC, et al. Bioorg Med Chem Lett. 2001 Oct 22;11(20):2691-6. doi: 10.1016/s0960-894x(01)00538-8. Bioorg Med Chem Lett. 2001. PMID: 11591503
Development of a potent thrombin receptor ligand.
Feng DM, Veber DF, Connolly TM, Condra C, Tang MJ, Nutt RF. Feng DM, et al. J Med Chem. 1995 Sep 29;38(20):4125-30. doi: 10.1021/jm00020a029. J Med Chem. 1995. PMID: 7562949
17 results