Fortin JS - Search Results

1

Alkylation potency and protein specificity of aromatic urea derivatives and bioisosteres as potential irreversible antagonists of the colchicine-binding site.

Fortin JS, Lacroix J, Desjardins M, Patenaude A, Petitclerc E, C-Gaudreault R. Fortin JS, et al. Bioorg Med Chem. 2007 Jul 1;15(13):4456-69. doi: 10.1016/j.bmc.2007.04.028. Epub 2007 Apr 22. Bioorg Med Chem. 2007. PMID: 17498960

2

ASK1-P38 pathway is important for anoikis induced by microtubule-targeting aryl chloroethylureas.

Fortin J, Patenaude A, Deschesnes RG, Côté MF, Petitclerc E, C-Gaudreault R. Fortin J, et al. J Pharm Pharm Sci. 2010;13(2):175-90. doi: 10.18433/j31g6c. J Pharm Pharm Sci. 2010. PMID: 20816004 Free article.

3

Cycloalkyl-substituted aryl chloroethylureas inhibiting cell cycle progression in G0/G1 phase and thioredoxin-1 nuclear translocation.

Fortin JS, Côté MF, Lacroix J, Patenaude A, Petitclerc E, C-Gaudreault R. Fortin JS, et al. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3526-31. doi: 10.1016/j.bmcl.2008.05.028. Epub 2008 May 10. Bioorg Med Chem Lett. 2008. PMID: 18502639

4

Aromatic 2-chloroethyl urea derivatives and bioisosteres. Part 2: Cytocidal activity and effects on the nuclear translocation of thioredoxin-1, and the cell cycle progression.

Fortin JS, Côté MF, Lacroix J, Petitclerc E, C-Gaudreault R. Fortin JS, et al. Bioorg Med Chem. 2008 Aug 1;16(15):7477-88. doi: 10.1016/j.bmc.2008.06.006. Epub 2008 Jun 10. Bioorg Med Chem. 2008. PMID: 18579387

5

Selective alkylation of beta(II)-tubulin and thioredoxin-1 by structurally related subsets of aryl chloroethylureas leading to either anti-microtubules or redox modulating agents.

Fortin JS, Côté MF, Lacroix J, Desjardins M, Petitclerc E, C-Gaudreault R. Fortin JS, et al. Bioorg Med Chem. 2008 Aug 1;16(15):7277-90. doi: 10.1016/j.bmc.2008.06.028. Epub 2008 Jun 20. Bioorg Med Chem. 2008. PMID: 18617414

6

Chloroethyl urea derivatives block tumour growth and thioredoxin-1 nuclear translocation.

Patenaude A, Fortin JS, Deschenes R, Côté MF, Lacroix J, C-Gaudreault R, Petitclerc E. Patenaude A, et al. Among authors: fortin js. Can J Physiol Pharmacol. 2010 Nov;88(11):1102-14. doi: 10.1139/y10-084. Can J Physiol Pharmacol. 2010. PMID: 21076498

7

Microtubule-destabilizing agents induce focal adhesion structure disorganization and anoikis in cancer cells.

Deschesnes RG, Patenaude A, Rousseau JL, Fortin JS, Ricard C, Côté MF, Huot J, C-Gaudreault R, Petitclerc E. Deschesnes RG, et al. Among authors: fortin js. J Pharmacol Exp Ther. 2007 Feb;320(2):853-64. doi: 10.1124/jpet.106.110957. Epub 2006 Nov 10. J Pharmacol Exp Ther. 2007. PMID: 17099073

8

Discovery of ethyl urea derivatives as inhibitors of islet amyloid polypeptide fibrillization and cytotoxicity.

Fortin JS, Benoit-Biancamano MO, C-Gaudreault R. Fortin JS, et al. Can J Physiol Pharmacol. 2016 Mar;94(3):341-6. doi: 10.1139/cjpp-2015-0204. Epub 2015 Sep 11. Can J Physiol Pharmacol. 2016. PMID: 26679837

9

Characterization of a pancreatic islet cell tumor in a polar bear (Ursus maritimus).

Fortin JS, Benoit-Biancamano MO. Fortin JS, et al. Zoo Biol. 2014 Sep-Oct;33(5):446-51. doi: 10.1002/zoo.21172. Epub 2014 Oct 1. Zoo Biol. 2014. PMID: 25273481

10

In vitro evaluation of hypoglycemic agents to target human islet amyloid polypeptide: a key protein involved in amyloid deposition and beta-cell loss.

Fortin JS, Benoit-Biancamano MO. Fortin JS, et al. Can J Diabetes. 2015 Oct;39(5):373-82. doi: 10.1016/j.jcjd.2015.01.291. Epub 2015 Apr 7. Can J Diabetes. 2015. PMID: 25862064

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