Annis DA - Search Results

1

Method for quantitative protein-ligand affinity measurements in compound mixtures.

Annis DA, Shipps GW Jr, Deng Y, Popovici-Müller J, Siddiqui MA, Curran PJ, Gowen M, Windsor WT. Annis DA, et al. Anal Chem. 2007 Jun 15;79(12):4538-42. doi: 10.1021/ac0702701. Epub 2007 May 15. Anal Chem. 2007. PMID: 17500537

2

A general technique to rank protein-ligand binding affinities and determine allosteric versus direct binding site competition in compound mixtures.

Annis DA, Nazef N, Chuang CC, Scott MP, Nash HM. Annis DA, et al. J Am Chem Soc. 2004 Dec 1;126(47):15495-503. doi: 10.1021/ja048365x. J Am Chem Soc. 2004. PMID: 15563178

3

Discovery and characterization of orthosteric and allosteric muscarinic M2 acetylcholine receptor ligands by affinity selection-mass spectrometry.

Whitehurst CE, Nazef N, Annis DA, Hou Y, Murphy DM, Spacciapoli P, Yao Z, Ziebell MR, Cheng CC, Shipps GW Jr, Felsch JS, Lau D, Nash HM. Whitehurst CE, et al. Among authors: annis da. J Biomol Screen. 2006 Mar;11(2):194-207. doi: 10.1177/1087057105284340. Epub 2006 Feb 20. J Biomol Screen. 2006. PMID: 16490772

4

Affinity selection-mass spectrometry screening techniques for small molecule drug discovery.

Annis DA, Nickbarg E, Yang X, Ziebell MR, Whitehurst CE. Annis DA, et al. Curr Opin Chem Biol. 2007 Oct;11(5):518-26. doi: 10.1016/j.cbpa.2007.07.011. Epub 2007 Oct 10. Curr Opin Chem Biol. 2007. PMID: 17931956 Review.

5

Affinity selection-mass spectrometry and its emerging application to the high throughput screening of G protein-coupled receptors.

Whitehurst CE, Annis DA. Whitehurst CE, et al. Among authors: annis da. Comb Chem High Throughput Screen. 2008 Jul;11(6):427-38. doi: 10.2174/138620708784911447. Comb Chem High Throughput Screen. 2008. PMID: 18673271 Review.

6

Inhibitors of the lipid phosphatase SHIP2 discovered by high-throughput affinity selection-mass spectrometry screening of combinatorial libraries.

Annis DA, Cheng CC, Chuang CC, McCarter JD, Nash HM, Nazef N, Rowe T, Kurzeja RJ, Shipps GW Jr. Annis DA, et al. Comb Chem High Throughput Screen. 2009 Sep;12(8):760-71. doi: 10.2174/138620709789104870. Epub 2009 Sep 1. Comb Chem High Throughput Screen. 2009. PMID: 19531013

7

Novel benzimidazole inhibitors bind to a unique site in the kinesin spindle protein motor domain.

Sheth PR, Shipps GW Jr, Seghezzi W, Smith CK, Chuang CC, Sanden D, Basso AD, Vilenchik L, Gray K, Annis DA, Nickbarg E, Ma Y, Lahue B, Herbst R, Le HV. Sheth PR, et al. Among authors: annis da. Biochemistry. 2010 Sep 28;49(38):8350-8. doi: 10.1021/bi1005283. Biochemistry. 2010. PMID: 20718440

8

Hydrogen exchange-mass spectrometry measures stapled peptide conformational dynamics and predicts pharmacokinetic properties.

Shi XE, Wales TE, Elkin C, Kawahata N, Engen JR, Annis DA. Shi XE, et al. Among authors: annis da. Anal Chem. 2013 Dec 3;85(23):11185-8. doi: 10.1021/ac403173p. Epub 2013 Nov 14. Anal Chem. 2013. PMID: 24215480 Free PMC article.

9

Discovery of novel, dual mechanism ERK inhibitors by affinity selection screening of an inactive kinase.

Deng Y, Shipps GW Jr, Cooper A, English JM, Annis DA, Carr D, Nan Y, Wang T, Zhu HY, Chuang CC, Dayananth P, Hruza AW, Xiao L, Jin W, Kirschmeier P, Windsor WT, Samatar AA. Deng Y, et al. Among authors: annis da. J Med Chem. 2014 Nov 13;57(21):8817-26. doi: 10.1021/jm500847m. Epub 2014 Oct 22. J Med Chem. 2014. PMID: 25313996

10

Solving the Competitive Binding Equilibria between Many Ligands: Application to High-Throughput Screening and Affinity Optimization.

Blay V, Otero-Muras I, Annis DA. Blay V, et al. Among authors: annis da. Anal Chem. 2020 Sep 15;92(18):12630-12638. doi: 10.1021/acs.analchem.0c02715. Epub 2020 Sep 3. Anal Chem. 2020. PMID: 32812419

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