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Drug design at peptide receptors: somatostatin receptor ligands.
Hannon JP, Nunn C, Stolz B, Bruns C, Weckbecker G, Lewis I, Troxler T, Hurth K, Hoyer D. Hannon JP, et al. Among authors: hoyer d. J Mol Neurosci. 2002 Feb-Apr;18(1-2):15-27. doi: 10.1385/JMN:18:1-2:15. J Mol Neurosci. 2002. PMID: 11931345 Review.
SAR of the arylpiperazine moiety of obeline somatostatin sst1 receptor antagonists.
Hurth K, Enz A, Floersheim P, Gentsch C, Hoyer D, Langenegger D, Neumann P, Pfäffli P, Sorg D, Swoboda R, Vassout A, Troxler T. Hurth K, et al. Among authors: hoyer d. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3988-91. doi: 10.1016/j.bmcl.2007.04.078. Epub 2007 Apr 30. Bioorg Med Chem Lett. 2007. PMID: 17512199
Discovery of novel non-peptidic beta-alanine piperazine amide derivatives and their optimization to achiral, easily accessible, potent and selective somatostatin sst1 receptor antagonists.
Troxler T, Hurth K, Mattes H, Prashad M, Schoeffter P, Langenegger D, Enz A, Hoyer D. Troxler T, et al. Among authors: hoyer d. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1305-9. doi: 10.1016/j.bmcl.2009.01.072. Epub 2009 Jan 27. Bioorg Med Chem Lett. 2009. PMID: 19208473
566 results