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Structure of the dimeric N-glycosylated form of fungal beta-N-acetylhexosaminidase revealed by computer modeling, vibrational spectroscopy, and biochemical studies.
Ettrich R, Kopecký V Jr, Hofbauerová K, Baumruk V, Novák P, Pompach P, Man P, Plíhal O, Kutý M, Kulik N, Sklenár J, Ryslavá H, Kren V, Bezouska K. Ettrich R, et al. Among authors: hofbauerova k. BMC Struct Biol. 2007 May 17;7:32. doi: 10.1186/1472-6807-7-32. BMC Struct Biol. 2007. PMID: 17509134 Free PMC article.
Large propeptides of fungal beta-N-acetylhexosaminidases are novel enzyme regulators that must be intracellularly processed to control activity, dimerization, and secretion into the extracellular environment.
Plíhal O, Sklenár J, Hofbauerová K, Novák P, Man P, Pompach P, Kavan D, Ryslavá H, Weignerová L, Charvátová-Pisvejcová A, Kren V, Bezouska K. Plíhal O, et al. Among authors: hofbauerova k. Biochemistry. 2007 Mar 13;46(10):2719-34. doi: 10.1021/bi061828m. Epub 2007 Feb 16. Biochemistry. 2007. PMID: 17302431
Crystallization and diffraction analysis of β-N-acetylhexosaminidase from Aspergillus oryzae.
Vaněk O, Brynda J, Hofbauerová K, Kukačka Z, Pachl P, Bezouška K, Rezáčová P. Vaněk O, et al. Among authors: hofbauerova k. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Apr 1;67(Pt 4):498-503. doi: 10.1107/S1744309111004945. Epub 2011 Mar 26. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21505251 Free PMC article.
Molecular architecture of mouse activating NKR-P1 receptors.
Kolenko P, Rozbeský D, Vaněk O, Kopecký V Jr, Hofbauerová K, Novák P, Pompach P, Hašek J, Skálová T, Bezouška K, Dohnálek J. Kolenko P, et al. Among authors: hofbauerova k. J Struct Biol. 2011 Sep;175(3):434-41. doi: 10.1016/j.jsb.2011.05.001. Epub 2011 May 12. J Struct Biol. 2011. PMID: 21600988
Crystal structure of native β-N-acetylhexosaminidase isolated from Aspergillus oryzae sheds light onto its substrate specificity, high stability, and regulation by propeptide.
Škerlová J, Bláha J, Pachl P, Hofbauerová K, Kukačka Z, Man P, Pompach P, Novák P, Otwinowski Z, Brynda J, Vaněk O, Řezáčová P. Škerlová J, et al. Among authors: hofbauerova k. FEBS J. 2018 Feb;285(3):580-598. doi: 10.1111/febs.14360. Epub 2017 Dec 30. FEBS J. 2018. PMID: 29239122 Free article.
41 results