Schiøtt B - Search Results

1

QSAR studies and pharmacophore identification for arylsubstituted cycloalkenecarboxylic acid methyl esters with affinity for the human dopamine transporter.

Christensen HS, Boye SV, Thinggaard J, Sinning S, Wiborg O, Schiøtt B, Bols M. Christensen HS, et al. Among authors: schiott b. Bioorg Med Chem. 2007 Aug 1;15(15):5262-74. doi: 10.1016/j.bmc.2007.05.015. Epub 2007 May 10. Bioorg Med Chem. 2007. PMID: 17517511

2

Binding of serotonin to the human serotonin transporter. Molecular modeling and experimental validation.

Celik L, Sinning S, Severinsen K, Hansen CG, Møller MS, Bols M, Wiborg O, Schiøtt B. Celik L, et al. Among authors: schiott b. J Am Chem Soc. 2008 Mar 26;130(12):3853-65. doi: 10.1021/ja076403h. Epub 2008 Mar 4. J Am Chem Soc. 2008. PMID: 18314975

3

Binding and orientation of tricyclic antidepressants within the central substrate site of the human serotonin transporter.

Sinning S, Musgaard M, Jensen M, Severinsen K, Celik L, Koldsø H, Meyer T, Bols M, Jensen HH, Schiøtt B, Wiborg O. Sinning S, et al. Among authors: schiott b. J Biol Chem. 2010 Mar 12;285(11):8363-74. doi: 10.1074/jbc.M109.045401. Epub 2009 Nov 30. J Biol Chem. 2010. PMID: 19948720 Free PMC article.

4

The two enantiomers of citalopram bind to the human serotonin transporter in reversed orientations.

Koldsø H, Severinsen K, Tran TT, Celik L, Jensen HH, Wiborg O, Schiøtt B, Sinning S. Koldsø H, et al. Among authors: schiott b. J Am Chem Soc. 2010 Feb 3;132(4):1311-22. doi: 10.1021/ja906923j. J Am Chem Soc. 2010. PMID: 20055463 Free article.

5

Unbiased simulations reveal the inward-facing conformation of the human serotonin transporter and Na(+) ion release.

Koldsø H, Noer P, Grouleff J, Autzen HE, Sinning S, Schiøtt B. Koldsø H, et al. Among authors: schiott b. PLoS Comput Biol. 2011 Oct;7(10):e1002246. doi: 10.1371/journal.pcbi.1002246. Epub 2011 Oct 27. PLoS Comput Biol. 2011. PMID: 22046120 Free PMC article.

6

Binding of the amphetamine-like 1-phenyl-piperazine to monoamine transporters.

Severinsen K, Kraft JF, Koldsø H, Vinberg KA, Rothman RB, Partilla JS, Wiborg O, Blough B, Schiøtt B, Sinning S. Severinsen K, et al. Among authors: schiott b. ACS Chem Neurosci. 2012 Sep 19;3(9):693-705. doi: 10.1021/cn300040f. Epub 2012 Jun 10. ACS Chem Neurosci. 2012. PMID: 23019496 Free PMC article.

7

Comparative modeling of the human monoamine transporters: similarities in substrate binding.

Koldsø H, Christiansen AB, Sinning S, Schiøtt B. Koldsø H, et al. Among authors: schiott b. ACS Chem Neurosci. 2013 Feb 20;4(2):295-309. doi: 10.1021/cn300148r. Epub 2012 Nov 8. ACS Chem Neurosci. 2013. PMID: 23421681 Free PMC article.

8

Binding of mazindol and analogs to the human serotonin and dopamine transporters.

Severinsen K, Koldsø H, Thorup KA, Schjøth-Eskesen C, Møller PT, Wiborg O, Jensen HH, Sinning S, Schiøtt B. Severinsen K, et al. Among authors: schiott b. Mol Pharmacol. 2014 Feb;85(2):208-17. doi: 10.1124/mol.113.088922. Epub 2013 Nov 8. Mol Pharmacol. 2014. PMID: 24214825

9

Binding of the multimodal antidepressant drug vortioxetine to the human serotonin transporter.

Andersen J, Ladefoged LK, Wang D, Kristensen TN, Bang-Andersen B, Kristensen AS, Schiøtt B, Strømgaard K. Andersen J, et al. Among authors: schiott b. ACS Chem Neurosci. 2015 Nov 18;6(11):1892-900. doi: 10.1021/acschemneuro.5b00225. Epub 2015 Oct 11. ACS Chem Neurosci. 2015. PMID: 26389667

10

Synthesis and inhibitory evaluation of 3-linked imipramines for the exploration of the S2 site of the human serotonin transporter.

Brinkø A, Larsen MT, Koldsø H, Besenbacher L, Kolind A, Schiøtt B, Sinning S, Jensen HH. Brinkø A, et al. Among authors: schiott b. Bioorg Med Chem. 2016 Jun 15;24(12):2725-38. doi: 10.1016/j.bmc.2016.04.039. Epub 2016 Apr 21. Bioorg Med Chem. 2016. PMID: 27160055

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