Enz A - Search Results

1

Pharmacokinetics and pharmacodynamics of the novel daily rivastigmine transdermal patch compared with twice-daily capsules in Alzheimer's disease patients.

Lefèvre G, Sedek G, Jhee SS, Leibowitz MT, Huang HL, Enz A, Maton S, Ereshefsky L, Pommier F, Schmidli H, Appel-Dingemanse S. Lefèvre G, et al. Among authors: enz a. Clin Pharmacol Ther. 2008 Jan;83(1):106-14. doi: 10.1038/sj.clpt.6100242. Epub 2007 May 23. Clin Pharmacol Ther. 2008. PMID: 17522596 Clinical Trial.

2

Lefèvre G, Büche M, Sedek G, Maton S, Enz A, Lorch U, Sagan C, Appel-Dingemanse S. Lefèvre G, et al. Among authors: enz a. J Clin Pharmacol. 2009 Apr;49(4):430-43. doi: 10.1177/0091270008330161. Epub 2009 Feb 26. J Clin Pharmacol. 2009. PMID: 19246725 Clinical Trial.

3

Dose-dependent CSF acetylcholinesterase inhibition by SDZ ENA 713 in Alzheimer's disease.

Cutler NR, Polinsky RJ, Sramek JJ, Enz A, Jhee SS, Mancione L, Hourani J, Zolnouni P. Cutler NR, et al. Among authors: enz a. Acta Neurol Scand. 1998 Apr;97(4):244-50. doi: 10.1111/j.1600-0404.1998.tb00645.x. Acta Neurol Scand. 1998. PMID: 9576639 Clinical Trial.

4

A simple, rapid and sensitive method for simultaneous determination of rivastigmine and its major metabolite NAP 226-90 in rat brain and plasma by reversed-phase liquid chromatography coupled to electrospray ionization mass spectrometry.

Enz A, Chappuis A, Dattler A. Enz A, et al. Biomed Chromatogr. 2004 Apr;18(3):160-6. doi: 10.1002/bmc.304. Biomed Chromatogr. 2004. PMID: 15103701

5

Co-administration of memantine has no effect on the in vitro or ex vivo determined acetylcholinesterase inhibition of rivastigmine in the rat brain.

Enz A, Gentsch C. Enz A, et al. Neuropharmacology. 2004 Sep;47(3):408-13. doi: 10.1016/j.neuropharm.2004.04.009. Neuropharmacology. 2004. PMID: 15275830

6

A study paradigm allowing comparison of multiple high-resolution rCBV-maps for the examination of drug effects.

Rausch M, Gentsch C, Enz A, Baumann D, Rudin M. Rausch M, et al. Among authors: enz a. NMR Biomed. 2005 Jun;18(4):260-8. doi: 10.1002/nbm.956. NMR Biomed. 2005. PMID: 15759291

7

Brain selective inhibition of acetylcholinesterase: a novel approach to therapy for Alzheimer's disease.

Enz A, Amstutz R, Boddeke H, Gmelin G, Malanowski J. Enz A, et al. Prog Brain Res. 1993;98:431-8. doi: 10.1016/s0079-6123(08)62429-2. Prog Brain Res. 1993. PMID: 8248533 Review.

Clinico-pharmacological studies with SDZ ENA 713 have been performed in healthy volunteers; while central activity was clearly demonstrated in an EEG-sleep study (Holsboer et al., 1992), no prohibitive peripheral side effects were seen, confirming in humans the results obtained i …

Clinico-pharmacological studies with SDZ ENA 713 have been performed in healthy volunteers; while central activity was clearly demonstrated …

8

Inhibition of acetyl- and butyryl-cholinesterase in the cerebrospinal fluid of patients with Alzheimer's disease by rivastigmine: correlation with cognitive benefit.

Giacobini E, Spiegel R, Enz A, Veroff AE, Cutler NR. Giacobini E, et al. Among authors: enz a. J Neural Transm (Vienna). 2002 Jul;109(7-8):1053-65. doi: 10.1007/s007020200089. J Neural Transm (Vienna). 2002. PMID: 12111443 Clinical Trial.

9

N1phenethyl-norcymserine, a selective butyrylcholinesterase inhibitor, increases acetylcholine release in rat cerebral cortex: a comparison with donepezil and rivastigmine.

Cerbai F, Giovannini MG, Melani C, Enz A, Pepeu G. Cerbai F, et al. Among authors: enz a. Eur J Pharmacol. 2007 Oct 31;572(2-3):142-50. doi: 10.1016/j.ejphar.2007.06.053. Epub 2007 Jul 4. Eur J Pharmacol. 2007. PMID: 17643410

10

Preferential cerebrospinal fluid acetylcholinesterase inhibition by rivastigmine in humans.

Kennedy JS, Polinsky RJ, Johnson B, Loosen P, Enz A, Laplanche R, Schmidt D, Mancione LC, Parris WC, Ebert MH. Kennedy JS, et al. Among authors: enz a. J Clin Psychopharmacol. 1999 Dec;19(6):513-21. doi: 10.1097/00004714-199912000-00005. J Clin Psychopharmacol. 1999. PMID: 10587286

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