Cook SJ - Search Results

1

ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL.

Ewings KE, Hadfield-Moorhouse K, Wiggins CM, Wickenden JA, Balmanno K, Gilley R, Degenhardt K, White E, Cook SJ. Ewings KE, et al. Among authors: cook sj. EMBO J. 2007 Jun 20;26(12):2856-67. doi: 10.1038/sj.emboj.7601723. Epub 2007 May 24. EMBO J. 2007. PMID: 17525735 Free PMC article.

2

Sustained MAP kinase activation is required for the expression of cyclin D1, p21Cip1 and a subset of AP-1 proteins in CCL39 cells.

Balmanno K, Cook SJ. Balmanno K, et al. Among authors: cook sj. Oncogene. 1999 May 20;18(20):3085-97. doi: 10.1038/sj.onc.1202647. Oncogene. 1999. PMID: 10340380

3

Regulation of cell cycle re-entry by growth, survival and stress signalling pathways.

Cook SJ, Balmanno K, Garner A, Millar T, Taverner C, Todd D. Cook SJ, et al. Biochem Soc Trans. 2000 Feb;28(2):233-40. doi: 10.1042/bst0280233. Biochem Soc Trans. 2000. PMID: 10816134 Review.

4

Delta MEKK3:ER* activation induces a p38 alpha/beta 2-dependent cell cycle arrest at the G2 checkpoint.

Garner AP, Weston CR, Todd DE, Balmanno K, Cook SJ. Garner AP, et al. Among authors: cook sj. Oncogene. 2002 Nov 21;21(53):8089-104. doi: 10.1038/sj.onc.1206000. Oncogene. 2002. PMID: 12444545

5

Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways.

Weston CR, Balmanno K, Chalmers C, Hadfield K, Molton SA, Ley R, Wagner EF, Cook SJ. Weston CR, et al. Among authors: cook sj. Oncogene. 2003 Mar 6;22(9):1281-93. doi: 10.1038/sj.onc.1206261. Oncogene. 2003. PMID: 12618753

6

Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

Ley R, Balmanno K, Hadfield K, Weston C, Cook SJ. Ley R, et al. Among authors: cook sj. J Biol Chem. 2003 May 23;278(21):18811-6. doi: 10.1074/jbc.M301010200. Epub 2003 Mar 19. J Biol Chem. 2003. PMID: 12646560 Free article.

7

Thrombin inhibits Bim (Bcl-2-interacting mediator of cell death) expression and prevents serum-withdrawal-induced apoptosis via protease-activated receptor 1.

Chalmers CJ, Balmanno K, Hadfield K, Ley R, Cook SJ. Chalmers CJ, et al. Among authors: cook sj. Biochem J. 2003 Oct 1;375(Pt 1):99-109. doi: 10.1042/BJ20030346. Biochem J. 2003. PMID: 12844349 Free PMC article.

8

Selective activation of the c-Jun N-terminal kinase (JNK) pathway fails to elicit Bax activation or apoptosis unless the phosphoinositide 3'-kinase (PI3K) pathway is inhibited.

Molton SA, Todd DE, Cook SJ. Molton SA, et al. Among authors: cook sj. Oncogene. 2003 Jul 24;22(30):4690-701. doi: 10.1038/sj.onc.1206692. Oncogene. 2003. PMID: 12879014

9

DeltaRaf-1:ER* bypasses the cyclic AMP block of extracellular signal-regulated kinase 1 and 2 activation but not CDK2 activation or cell cycle reentry.

Balmanno K, Millar T, McMahon M, Cook SJ. Balmanno K, et al. Among authors: cook sj. Mol Cell Biol. 2003 Dec;23(24):9303-17. doi: 10.1128/MCB.23.24.9303-9317.2003. Mol Cell Biol. 2003. PMID: 14645540 Free PMC article.

10

Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover.

Ley R, Ewings KE, Hadfield K, Howes E, Balmanno K, Cook SJ. Ley R, et al. Among authors: cook sj. J Biol Chem. 2004 Mar 5;279(10):8837-47. doi: 10.1074/jbc.M311578200. Epub 2003 Dec 17. J Biol Chem. 2004. PMID: 14681225 Free article.

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