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Page 1
CADASIL mutations impair Notch3 glycosylation by Fringe.
Arboleda-Velasquez JF, Rampal R, Fung E, Darland DC, Liu M, Martinez MC, Donahue CP, Navarro-Gonzalez MF, Libby P, D'Amore PA, Aikawa M, Haltiwanger RS, Kosik KS. Arboleda-Velasquez JF, et al. Hum Mol Genet. 2005 Jun 15;14(12):1631-9. doi: 10.1093/hmg/ddi171. Epub 2005 Apr 27. Hum Mol Genet. 2005. PMID: 15857853
Linking Notch signaling to ischemic stroke.
Arboleda-Velasquez JF, Zhou Z, Shin HK, Louvi A, Kim HH, Savitz SI, Liao JK, Salomone S, Ayata C, Moskowitz MA, Artavanis-Tsakonas S. Arboleda-Velasquez JF, et al. Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4856-61. doi: 10.1073/pnas.0709867105. Epub 2008 Mar 17. Proc Natl Acad Sci U S A. 2008. PMID: 18347334 Free PMC article.
Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease.
Arboleda-Velasquez JF, Manent J, Lee JH, Tikka S, Ospina C, Vanderburg CR, Frosch MP, Rodríguez-Falcón M, Villen J, Gygi S, Lopera F, Kalimo H, Moskowitz MA, Ayata C, Louvi A, Artavanis-Tsakonas S. Arboleda-Velasquez JF, et al. Proc Natl Acad Sci U S A. 2011 May 24;108(21):E128-35. doi: 10.1073/pnas.1101964108. Epub 2011 May 9. Proc Natl Acad Sci U S A. 2011. PMID: 21555590 Free PMC article.
Notch signaling functions in retinal pericyte survival.
Arboleda-Velasquez JF, Primo V, Graham M, James A, Manent J, D'Amore PA. Arboleda-Velasquez JF, et al. Invest Ophthalmol Vis Sci. 2014 Jul 11;55(8):5191-9. doi: 10.1167/iovs.14-14046. Invest Ophthalmol Vis Sci. 2014. PMID: 25015359 Free PMC article.
CADASIL: a critical look at a Notch disease.
Louvi A, Arboleda-Velasquez JF, Artavanis-Tsakonas S. Louvi A, et al. Dev Neurosci. 2006;28(1-2):5-12. doi: 10.1159/000090748. Dev Neurosci. 2006. PMID: 16508299 Review.
Therapeutic antibody targeting of Notch3 signaling prevents mural cell loss in CADASIL.
Machuca-Parra AI, Bigger-Allen AA, Sanchez AV, Boutabla A, Cardona-Vélez J, Amarnani D, Saint-Geniez M, Siebel CW, Kim LA, D'Amore PA, Arboleda-Velasquez JF. Machuca-Parra AI, et al. J Exp Med. 2017 Aug 7;214(8):2271-2282. doi: 10.1084/jem.20161715. Epub 2017 Jul 11. J Exp Med. 2017. PMID: 28698285 Free PMC article.
57 results