Yang J - Search Results

1

Interleukin-6 alters the cellular responsiveness to clopidogrel, irinotecan, and oseltamivir by suppressing the expression of carboxylesterases HCE1 and HCE2.

Yang J, Shi D, Yang D, Song X, Yan B. Yang J, et al. Among authors: yang d. Mol Pharmacol. 2007 Sep;72(3):686-94. doi: 10.1124/mol.107.036889. Epub 2007 May 30. Mol Pharmacol. 2007. PMID: 17537833

2

Byakangelicin induces cytochrome P450 3A4 expression via transactivation of pregnane X receptors in human hepatocytes.

Yang J, Luan X, Gui H, Yan P, Yang D, Song X, Liu W, Hu G, Yan B. Yang J, et al. Among authors: yang d. Br J Pharmacol. 2011 Jan;162(2):441-51. doi: 10.1111/j.1476-5381.2010.01069.x. Br J Pharmacol. 2011. PMID: 20942813 Free PMC article.

3

17β-estradiol suppresses carboxylesterases by activating c-Jun/AP-1 pathway in primary human and mouse hepatocytes.

Wu L, Hafiz MZ, Guan Y, He S, Xiong J, Liu W, Yan B, Li X, Yang J. Wu L, et al. Among authors: yang j. Eur J Pharmacol. 2018 Jan 15;819:98-107. doi: 10.1016/j.ejphar.2017.11.036. Epub 2017 Nov 23. Eur J Pharmacol. 2018. PMID: 29175444

4

Anti-influenza prodrug oseltamivir is activated by carboxylesterase human carboxylesterase 1, and the activation is inhibited by antiplatelet agent clopidogrel.

Shi D, Yang J, Yang D, LeCluyse EL, Black C, You L, Akhlaghi F, Yan B. Shi D, et al. Among authors: yang d, yang j. J Pharmacol Exp Ther. 2006 Dec;319(3):1477-84. doi: 10.1124/jpet.106.111807. Epub 2006 Sep 11. J Pharmacol Exp Ther. 2006. PMID: 16966469

5

Pregnane X receptor is required for interleukin-6-mediated down-regulation of cytochrome P450 3A4 in human hepatocytes.

Yang J, Hao C, Yang D, Shi D, Song X, Luan X, Hu G, Yan B. Yang J, et al. Among authors: yang d. Toxicol Lett. 2010 Sep 1;197(3):219-26. doi: 10.1016/j.toxlet.2010.06.003. Epub 2010 Jun 9. Toxicol Lett. 2010. PMID: 20538049 Free PMC article.

6

Lipopolysaccharide down-regulates carbolesterases 1 and 2 and reduces hydrolysis activity in vitro and in vivo via p38MAPK-NF-κB pathway.

Mao Z, Li Y, Peng Y, Luan X, Gui H, Feng X, Hu G, Shen J, Yan B, Yang J. Mao Z, et al. Among authors: yang j. Toxicol Lett. 2011 Mar 25;201(3):213-20. doi: 10.1016/j.toxlet.2011.01.002. Epub 2011 Jan 13. Toxicol Lett. 2011. PMID: 21237253 Free PMC article.

7

Interleukin-6 Induces DEC1, Promotes DEC1 Interaction with RXRα and Suppresses the Expression of PXR, CAR and Their Target Genes.

Ning R, Zhan Y, He S, Hu J, Zhu Z, Hu G, Yan B, Yang J, Liu W. Ning R, et al. Among authors: yang j. Front Pharmacol. 2017 Nov 28;8:866. doi: 10.3389/fphar.2017.00866. eCollection 2017. Front Pharmacol. 2017. PMID: 29234281 Free PMC article.

8

Photochemotherapeutic agent 8-methoxypsoralen induces cytochrome P450 3A4 and carboxylesterase HCE2: evidence on an involvement of the pregnane X receptor.

Yang J, Yan B. Yang J, et al. Toxicol Sci. 2007 Jan;95(1):13-22. doi: 10.1093/toxsci/kfl120. Epub 2006 Sep 26. Toxicol Sci. 2007. PMID: 17003103 Free PMC article.

9

Dexamethasone suppresses the expression of multiple rat carboxylesterases through transcriptional repression: evidence for an involvement of the glucocorticoid receptor.

Shi D, Yang J, Yang D, Yan B. Shi D, et al. Among authors: yang d, yang j. Toxicology. 2008 Dec 5;254(1-2):97-105. doi: 10.1016/j.tox.2008.09.019. Epub 2008 Sep 30. Toxicology. 2008. PMID: 18938207 Free PMC article.

10

Antiplatelet agents aspirin and clopidogrel are hydrolyzed by distinct carboxylesterases, and clopidogrel is transesterificated in the presence of ethyl alcohol.

Tang M, Mukundan M, Yang J, Charpentier N, LeCluyse EL, Black C, Yang D, Shi D, Yan B. Tang M, et al. Among authors: yang d, yang j. J Pharmacol Exp Ther. 2006 Dec;319(3):1467-76. doi: 10.1124/jpet.106.110577. Epub 2006 Aug 30. J Pharmacol Exp Ther. 2006. PMID: 16943252

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