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Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis.
Buckbinder L, Crawford DT, Qi H, Ke HZ, Olson LM, Long KR, Bonnette PC, Baumann AP, Hambor JE, Grasser WA 3rd, Pan LC, Owen TA, Luzzio MJ, Hulford CA, Gebhard DF, Paralkar VM, Simmons HA, Kath JC, Roberts WG, Smock SL, Guzman-Perez A, Brown TA, Li M. Buckbinder L, et al. Among authors: long kr. Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10619-24. doi: 10.1073/pnas.0701421104. Epub 2007 May 30. Proc Natl Acad Sci U S A. 2007. PMID: 17537919 Free PMC article.
SGLT2-independent effects of canagliflozin on NHE3 and mitochondrial complex I activity inhibit proximal tubule fluid transport and albumin uptake.
Albalawy WN, Youm EB, Shipman KE, Trull KJ, Baty CJ, Long KR, Rbaibi Y, Wang XP, Fagunloye OG, White KA, Jurczak MJ, Kashlan OB, Weisz OA. Albalawy WN, et al. Among authors: long kr. Am J Physiol Renal Physiol. 2024 Jun 1;326(6):F1041-F1053. doi: 10.1152/ajprenal.00005.2024. Epub 2024 Apr 25. Am J Physiol Renal Physiol. 2024. PMID: 38660713
87 results