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142 results

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Optimized Substrate Positioning Enables Switches in the C-H Cleavage Site and Reaction Outcome in the Hydroxylation-Epoxidation Sequence Catalyzed by Hyoscyamine 6β-Hydroxylase.
Wenger ES, Martinie RJ, Ushimaru R, Pollock CJ, Sil D, Li A, Hoang N, Palowitch GM, Graham BP, Schaperdoth I, Burke EJ, Maggiolo AO, Chang WC, Allen BD, Krebs C, Silakov A, Boal AK, Bollinger JM Jr. Wenger ES, et al. Among authors: bollinger jm jr. J Am Chem Soc. 2024 Sep 4;146(35):24271-24287. doi: 10.1021/jacs.4c04406. Epub 2024 Aug 22. J Am Chem Soc. 2024. PMID: 39172701 Free PMC article.
Probing Ferryl Reactivity in a Nonheme Iron Oxygenase Using an Expanded Genetic Code.
Hardy FJ, Quesne MG, Gérard EF, Zhao J, Ortmayer M, Taylor CJ, Ali HS, Slater JW, Levy CW, Heyes DJ, Bollinger JM Jr, de Visser SP, Green AP. Hardy FJ, et al. Among authors: bollinger jm jr. ACS Catal. 2024 Jul 20;14(15):11584-11590. doi: 10.1021/acscatal.4c02365. eCollection 2024 Aug 2. ACS Catal. 2024. PMID: 39114090 Free PMC article.
An Unusual Ferryl Intermediate and Its Implications for the Mechanism of Oxacyclization by the Loline-Producing Iron(II)- and 2-Oxoglutarate-Dependent Oxygenase, LolO.
Pan J, Wenger ES, Lin CY, Zhang B, Sil D, Schaperdoth I, Saryazdi S, Grossman RB, Krebs C, Bollinger JM Jr. Pan J, et al. Among authors: bollinger jm jr. Biochemistry. 2024 Jul 2;63(13):1674-1683. doi: 10.1021/acs.biochem.4c00166. Epub 2024 Jun 19. Biochemistry. 2024. PMID: 38898603 Free PMC article.
Synergistic Binding of the Halide and Cationic Prime Substrate of the l-Lysine 4-Chlorinase, BesD, in Both Ferrous and Ferryl States.
Slater JW, Neugebauer ME, McBride MJ, Sil D, Lin CY, Katch BJ, Boal AK, Chang MCY, Silakov A, Krebs C, Bollinger JM Jr. Slater JW, et al. Among authors: bollinger jm jr. bioRxiv [Preprint]. 2023 May 2:2023.05.02.539147. doi: 10.1101/2023.05.02.539147. bioRxiv. 2023. Update in: Biochemistry. 2023 Aug 15;62(16):2480-2491. doi: 10.1021/acs.biochem.3c00248. PMID: 37205437 Free PMC article. Updated. Preprint.
Substrate-Triggered μ-Peroxodiiron(III) Intermediate in the 4-Chloro-l-Lysine-Fragmenting Heme-Oxygenase-like Diiron Oxidase (HDO) BesC: Substrate Dissociation from, and C4 Targeting by, the Intermediate.
McBride MJ, Nair MA, Sil D, Slater JW, Neugebauer ME, Chang MCY, Boal AK, Krebs C, Bollinger JM Jr. McBride MJ, et al. Among authors: bollinger jm jr. Biochemistry. 2022 Apr 19;61(8):689-702. doi: 10.1021/acs.biochem.1c00774. Epub 2022 Apr 5. Biochemistry. 2022. PMID: 35380785 Free PMC article.
142 results