Tan DS - Search Results

1

Exploiting ligand conformation in selective inhibition of non-ribosomal peptide synthetase amino acid adenylation with designed macrocyclic small molecules.

Cisar JS, Ferreras JA, Soni RK, Quadri LE, Tan DS. Cisar JS, et al. Among authors: tan ds. J Am Chem Soc. 2007 Jun 27;129(25):7752-3. doi: 10.1021/ja0721521. Epub 2007 Jun 2. J Am Chem Soc. 2007. PMID: 17542590 Free PMC article.

2

Stereocontrolled synthesis of spiroketals via a remarkable methanol-induced kinetic spirocyclization reaction.

Potuzak JS, Moilanen SB, Tan DS. Potuzak JS, et al. Among authors: tan ds. J Am Chem Soc. 2005 Oct 12;127(40):13796-7. doi: 10.1021/ja055033z. J Am Chem Soc. 2005. PMID: 16201793

3

Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis.

Ferreras JA, Ryu JS, Di Lello F, Tan DS, Quadri LE. Ferreras JA, et al. Among authors: tan ds. Nat Chem Biol. 2005 Jun;1(1):29-32. doi: 10.1038/nchembio706. Epub 2005 May 24. Nat Chem Biol. 2005. PMID: 16407990

4

Diversity-oriented synthesis: exploring the intersections between chemistry and biology.

Tan DS. Tan DS. Nat Chem Biol. 2005 Jul;1(2):74-84. doi: 10.1038/nchembio0705-74. Nat Chem Biol. 2005. PMID: 16408003 Review.

5

Stereocontrolled synthesis of spiroketals via Ti(Oi-Pr)4-mediated kinetic spirocyclization of glycal epoxides with retention of configuration.

Moilanen SB, Potuzak JS, Tan DS. Moilanen SB, et al. Among authors: tan ds. J Am Chem Soc. 2006 Feb 15;128(6):1792-3. doi: 10.1021/ja057908f. J Am Chem Soc. 2006. PMID: 16464069 Free PMC article.

6

Mycobacterial phenolic glycolipid virulence factor biosynthesis: mechanism and small-molecule inhibition of polyketide chain initiation.

Ferreras JA, Stirrett KL, Lu X, Ryu JS, Soll CE, Tan DS, Quadri LE. Ferreras JA, et al. Among authors: tan ds. Chem Biol. 2008 Jan;15(1):51-61. doi: 10.1016/j.chembiol.2007.11.010. Epub 2007 Dec 27. Chem Biol. 2008. PMID: 18158259 Free PMC article.

7

Small molecule inhibition of microbial natural product biosynthesis-an emerging antibiotic strategy.

Cisar JS, Tan DS. Cisar JS, et al. Among authors: tan ds. Chem Soc Rev. 2008 Jul;37(7):1320-9. doi: 10.1039/b702780j. Epub 2008 May 21. Chem Soc Rev. 2008. PMID: 18568158 Free PMC article. Review.

8

Designed semisynthetic protein inhibitors of Ub/Ubl E1 activating enzymes.

Lu X, Olsen SK, Capili AD, Cisar JS, Lima CD, Tan DS. Lu X, et al. Among authors: tan ds. J Am Chem Soc. 2010 Feb 17;132(6):1748-9. doi: 10.1021/ja9088549. J Am Chem Soc. 2010. PMID: 20099854 Free PMC article.

9

Hydrogen-bonding catalysis and inhibition by simple solvents in the stereoselective kinetic epoxide-opening spirocyclization of glycal epoxides to form spiroketals.

Wurst JM, Liu G, Tan DS. Wurst JM, et al. Among authors: tan ds. J Am Chem Soc. 2011 May 25;133(20):7916-25. doi: 10.1021/ja201249c. Epub 2011 May 3. J Am Chem Soc. 2011. PMID: 21539313 Free PMC article.

10

A diversity-oriented synthesis approach to macrocycles via oxidative ring expansion.

Kopp F, Stratton CF, Akella LB, Tan DS. Kopp F, et al. Among authors: tan ds. Nat Chem Biol. 2012 Mar 11;8(4):358-65. doi: 10.1038/nchembio.911. Nat Chem Biol. 2012. PMID: 22406518 Free PMC article.

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