Stammers DK - Search Results

1

Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy.

Cader MZ, Ren J, James PA, Bird LE, Talbot K, Stammers DK. Cader MZ, et al. Among authors: stammers dk. FEBS Lett. 2007 Jun 26;581(16):2959-64. doi: 10.1016/j.febslet.2007.05.046. Epub 2007 May 29. FEBS Lett. 2007. PMID: 17544401 Free article.

2

Crystal structure of CC3 (TIP30): implications for its role as a tumor suppressor.

El Omari K, Bird LE, Nichols CE, Ren J, Stammers DK. El Omari K, et al. Among authors: stammers dk. J Biol Chem. 2005 May 6;280(18):18229-36. doi: 10.1074/jbc.M501113200. Epub 2005 Feb 22. J Biol Chem. 2005. PMID: 15728189 Free article.

3

Molecular architecture and ligand recognition determinants for T4 RNA ligase.

El Omari K, Ren J, Bird LE, Bona MK, Klarmann G, LeGrice SF, Stammers DK. El Omari K, et al. Among authors: stammers dk. J Biol Chem. 2006 Jan 20;281(3):1573-9. doi: 10.1074/jbc.M509658200. Epub 2005 Nov 1. J Biol Chem. 2006. PMID: 16263720 Free article.

4

Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138.

Ren J, Nichols CE, Stamp A, Chamberlain PP, Ferris R, Weaver KL, Short SA, Stammers DK. Ren J, et al. Among authors: stammers dk. FEBS J. 2006 Aug;273(16):3850-60. doi: 10.1111/j.1742-4658.2006.05392.x. FEBS J. 2006. PMID: 16911530 Free article.

5

Structural basis for drug resistance mechanisms for non-nucleoside inhibitors of HIV reverse transcriptase.

Ren J, Stammers DK. Ren J, et al. Among authors: stammers dk. Virus Res. 2008 Jun;134(1-2):157-70. doi: 10.1016/j.virusres.2007.12.018. Epub 2008 Mar 3. Virus Res. 2008. PMID: 18313784 Review.

6

Crystal structure of SANOS, a bacterial nitric oxide synthase oxygenase protein from Staphylococcus aureus.

Bird LE, Ren J, Zhang J, Foxwell N, Hawkins AR, Charles IG, Stammers DK. Bird LE, et al. Among authors: stammers dk. Structure. 2002 Dec;10(12):1687-96. doi: 10.1016/s0969-2126(02)00911-5. Structure. 2002. PMID: 12467576 Free article.

7

Crystal structure of varicella zoster virus thymidine kinase.

Bird LE, Ren J, Wright A, Leslie KD, Degrève B, Balzarini J, Stammers DK. Bird LE, et al. Among authors: stammers dk. J Biol Chem. 2003 Jul 4;278(27):24680-7. doi: 10.1074/jbc.M302025200. Epub 2003 Apr 9. J Biol Chem. 2003. PMID: 12686543 Free article.

8

Crystallographic studies of shikimate binding and induced conformational changes in Mycobacterium tuberculosis shikimate kinase.

Dhaliwal B, Nichols CE, Ren J, Lockyer M, Charles I, Hawkins AR, Stammers DK. Dhaliwal B, et al. Among authors: stammers dk. FEBS Lett. 2004 Sep 10;574(1-3):49-54. doi: 10.1016/j.febslet.2004.08.005. FEBS Lett. 2004. PMID: 15358538 Free article.

9

Mutations distal to the substrate site can affect varicella zoster virus thymidine kinase activity: implications for drug design.

El Omari K, Liekens S, Bird LE, Balzarini J, Stammers DK. El Omari K, et al. Among authors: stammers dk. Mol Pharmacol. 2006 Jun;69(6):1891-6. doi: 10.1124/mol.106.023002. Epub 2006 Mar 23. Mol Pharmacol. 2006. PMID: 16556772

10

Relationship of potency and resilience to drug resistant mutations for GW420867X revealed by crystal structures of inhibitor complexes for wild-type, Leu100Ile, Lys101Glu, and Tyr188Cys mutant HIV-1 reverse transcriptases.

Ren J, Nichols CE, Chamberlain PP, Weaver KL, Short SA, Chan JH, Kleim JP, Stammers DK. Ren J, et al. Among authors: stammers dk. J Med Chem. 2007 May 17;50(10):2301-9. doi: 10.1021/jm061117m. Epub 2007 Apr 19. J Med Chem. 2007. PMID: 17441703

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