Okuno Y - Search Results

1

Down-regulation of PU.1 by methylation of distal regulatory elements and the promoter is required for myeloma cell growth.

Tatetsu H, Ueno S, Hata H, Yamada Y, Takeya M, Mitsuya H, Tenen DG, Okuno Y. Tatetsu H, et al. Among authors: okuno y. Cancer Res. 2007 Jun 1;67(11):5328-36. doi: 10.1158/0008-5472.CAN-06-4265. Cancer Res. 2007. PMID: 17545613

2

Regulation of the PU.1 gene by distal elements.

Li Y, Okuno Y, Zhang P, Radomska HS, Chen H, Iwasaki H, Akashi K, Klemsz MJ, McKercher SR, Maki RA, Tenen DG. Li Y, et al. Among authors: okuno y. Blood. 2001 Nov 15;98(10):2958-65. doi: 10.1182/blood.v98.10.2958. Blood. 2001. PMID: 11698277 Free article.

3

Differential regulation of the human and murine CD34 genes in hematopoietic stem cells.

Okuno Y, Iwasaki H, Huettner CS, Radomska HS, Gonzalez DA, Tenen DG, Akashi K. Okuno Y, et al. Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6246-51. doi: 10.1073/pnas.092027799. Proc Natl Acad Sci U S A. 2002. PMID: 11983914 Free PMC article.

4

Transgenic targeting with regulatory elements of the human CD34 gene.

Radomska HS, Gonzalez DA, Okuno Y, Iwasaki H, Nagy A, Akashi K, Tenen DG, Huettner CS. Radomska HS, et al. Among authors: okuno y. Blood. 2002 Dec 15;100(13):4410-9. doi: 10.1182/blood-2002-02-0355. Epub 2002 Aug 15. Blood. 2002. PMID: 12393582 Free article.

5

Distal elements are critical for human CD34 expression in vivo.

Okuno Y, Huettner CS, Radomska HS, Petkova V, Iwasaki H, Akashi K, Tenen DG. Okuno Y, et al. Blood. 2002 Dec 15;100(13):4420-6. doi: 10.1182/blood-2002-03-0788. Epub 2002 Aug 22. Blood. 2002. PMID: 12393741 Free article.

6

Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.

Rosenbauer F, Wagner K, Kutok JL, Iwasaki H, Le Beau MM, Okuno Y, Akashi K, Fiering S, Tenen DG. Rosenbauer F, et al. Among authors: okuno y. Nat Genet. 2004 Jun;36(6):624-30. doi: 10.1038/ng1361. Epub 2004 May 16. Nat Genet. 2004. PMID: 15146183

7

Potential autoregulation of transcription factor PU.1 by an upstream regulatory element.

Okuno Y, Huang G, Rosenbauer F, Evans EK, Radomska HS, Iwasaki H, Akashi K, Moreau-Gachelin F, Li Y, Zhang P, Göttgens B, Tenen DG. Okuno Y, et al. Mol Cell Biol. 2005 Apr;25(7):2832-45. doi: 10.1128/MCB.25.7.2832-2845.2005. Mol Cell Biol. 2005. PMID: 15767686 Free PMC article.

8

Dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, induces apoptosis in multiple myeloma cells in an IkappaBalpha-independent manner.

Tatetsu H, Okuno Y, Nakamura M, Matsuno F, Sonoki T, Taniguchi I, Uneda S, Umezawa K, Mitsuya H, Hata H. Tatetsu H, et al. Among authors: okuno y. Mol Cancer Ther. 2005 Jul;4(7):1114-20. doi: 10.1158/1535-7163.MCT-04-0198. Mol Cancer Ther. 2005. PMID: 16020669

9

Activation of the endoplasmic reticulum stress pathway is associated with survival of myeloma cells.

Nakamura M, Gotoh T, Okuno Y, Tatetsu H, Sonoki T, Uneda S, Mori M, Mitsuya H, Hata H. Nakamura M, et al. Among authors: okuno y. Leuk Lymphoma. 2006 Mar;47(3):531-9. doi: 10.1080/10428190500312196. Leuk Lymphoma. 2006. PMID: 16396777

10

PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis.

Huang G, Zhang P, Hirai H, Elf S, Yan X, Chen Z, Koschmieder S, Okuno Y, Dayaram T, Growney JD, Shivdasani RA, Gilliland DG, Speck NA, Nimer SD, Tenen DG. Huang G, et al. Among authors: okuno y. Nat Genet. 2008 Jan;40(1):51-60. doi: 10.1038/ng.2007.7. Epub 2007 Nov 11. Nat Genet. 2008. PMID: 17994017

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