Westrick E - Search Results

1

Comparative preclinical activity of the folate-targeted Vinca alkaloid conjugates EC140 and EC145.

Leamon CP, Reddy JA, Vlahov IR, Westrick E, Parker N, Nicoson JS, Vetzel M. Leamon CP, et al. Among authors: westrick e. Int J Cancer. 2007 Oct 1;121(7):1585-92. doi: 10.1002/ijc.22853. Int J Cancer. 2007. PMID: 17551919

2

Synthesis and biological evaluation of EC72: a new folate-targeted chemotherapeutic.

Leamon CP, Reddy JA, Vlahov IR, Vetzel M, Parker N, Nicoson JS, Xu LC, Westrick E. Leamon CP, et al. Among authors: westrick e. Bioconjug Chem. 2005 Jul-Aug;16(4):803-11. doi: 10.1021/bc049709b. Bioconjug Chem. 2005. PMID: 16029021

3

Folate receptor specific anti-tumor activity of folate-mitomycin conjugates.

Reddy JA, Westrick E, Vlahov I, Howard SJ, Santhapuram HK, Leamon CP. Reddy JA, et al. Among authors: westrick e. Cancer Chemother Pharmacol. 2006 Aug;58(2):229-36. doi: 10.1007/s00280-005-0151-z. Epub 2005 Dec 6. Cancer Chemother Pharmacol. 2006. PMID: 16331500

4

Synthesis and biological evaluation of EC140: a novel folate-targeted vinca alkaloid conjugate.

Leamon CP, Reddy JA, Vlahov IR, Kleindl PJ, Vetzel M, Westrick E. Leamon CP, et al. Among authors: westrick e. Bioconjug Chem. 2006 Sep-Oct;17(5):1226-32. doi: 10.1021/bc060145g. Bioconjug Chem. 2006. PMID: 16984132

5

Preclinical pharmacokinetics, tissue distribution, and antitumor activity of a folate-hapten conjugate-targeted immunotherapy in hapten-immunized mice.

Lu Y, Xu LC, Parker N, Westrick E, Reddy JA, Vetzel M, Low PS, Leamon CP. Lu Y, et al. Among authors: westrick e. Mol Cancer Ther. 2006 Dec;5(12):3258-67. doi: 10.1158/1535-7163.MCT-06-0439. Mol Cancer Ther. 2006. PMID: 17172429

6

Preclinical evaluation of EC145, a folate-vinca alkaloid conjugate.

Reddy JA, Dorton R, Westrick E, Dawson A, Smith T, Xu LC, Vetzel M, Kleindl P, Vlahov IR, Leamon CP. Reddy JA, et al. Among authors: westrick e. Cancer Res. 2007 May 1;67(9):4434-42. doi: 10.1158/0008-5472.CAN-07-0033. Cancer Res. 2007. PMID: 17483358

7

Folate receptor-specific antitumor activity of EC131, a folate-maytansinoid conjugate.

Reddy JA, Westrick E, Santhapuram HK, Howard SJ, Miller ML, Vetzel M, Vlahov I, Chari RV, Goldmacher VS, Leamon CP. Reddy JA, et al. Among authors: westrick e. Cancer Res. 2007 Jul 1;67(13):6376-82. doi: 10.1158/0008-5472.CAN-06-3894. Cancer Res. 2007. PMID: 17616697

8

Folate-targeted dinitrophenyl hapten immunotherapy: effect of linker chemistry on antitumor activity and allergic potential.

Lu Y, You F, Vlahov I, Westrick E, Fan M, Low PS, Leamon CP. Lu Y, et al. Among authors: westrick e. Mol Pharm. 2007 Sep-Oct;4(5):695-706. doi: 10.1021/mp070050b. Epub 2007 Sep 5. Mol Pharm. 2007. PMID: 17784727

9

Preclinical antitumor activity of a novel folate-targeted dual drug conjugate.

Leamon CP, Reddy JA, Vlahov IR, Westrick E, Dawson A, Dorton R, Vetzel M, Santhapuram HK, Wang Y. Leamon CP, et al. Among authors: westrick e. Mol Pharm. 2007 Sep-Oct;4(5):659-67. doi: 10.1021/mp070049c. Epub 2007 Sep 18. Mol Pharm. 2007. PMID: 17874843

10

Impact of high and low folate diets on tissue folate receptor levels and antitumor responses toward folate-drug conjugates.

Leamon CP, Reddy JA, Dorton R, Bloomfield A, Emsweller K, Parker N, Westrick E. Leamon CP, et al. Among authors: westrick e. J Pharmacol Exp Ther. 2008 Dec;327(3):918-25. doi: 10.1124/jpet.108.143206. Epub 2008 Sep 12. J Pharmacol Exp Ther. 2008. PMID: 18791065

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