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309 results

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Page 1
A microRNA component of the p53 tumour suppressor network.
He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y, Xue W, Zender L, Magnus J, Ridzon D, Jackson AL, Linsley PS, Chen C, Lowe SW, Cleary MA, Hannon GJ. He L, et al. Among authors: linsley ps. Nature. 2007 Jun 28;447(7148):1130-4. doi: 10.1038/nature05939. Epub 2007 Jun 6. Nature. 2007. PMID: 17554337 Free PMC article.
Expression profiling reveals off-target gene regulation by RNAi.
Jackson AL, Bartz SR, Schelter J, Kobayashi SV, Burchard J, Mao M, Li B, Cavet G, Linsley PS. Jackson AL, et al. Among authors: linsley ps. Nat Biotechnol. 2003 Jun;21(6):635-7. doi: 10.1038/nbt831. Epub 2003 May 18. Nat Biotechnol. 2003. PMID: 12754523
A large-scale RNAi screen in human cells identifies new components of the p53 pathway.
Berns K, Hijmans EM, Mullenders J, Brummelkamp TR, Velds A, Heimerikx M, Kerkhoven RM, Madiredjo M, Nijkamp W, Weigelt B, Agami R, Ge W, Cavet G, Linsley PS, Beijersbergen RL, Bernards R. Berns K, et al. Among authors: linsley ps. Nature. 2004 Mar 25;428(6981):431-7. doi: 10.1038/nature02371. Nature. 2004. PMID: 15042092
Synthetic shRNAs as potent RNAi triggers.
Siolas D, Lerner C, Burchard J, Ge W, Linsley PS, Paddison PJ, Hannon GJ, Cleary MA. Siolas D, et al. Among authors: linsley ps. Nat Biotechnol. 2005 Feb;23(2):227-31. doi: 10.1038/nbt1052. Epub 2004 Dec 26. Nat Biotechnol. 2005. PMID: 15619616
Minimizing the risk of reporting false positives in large-scale RNAi screens.
Echeverri CJ, Beachy PA, Baum B, Boutros M, Buchholz F, Chanda SK, Downward J, Ellenberg J, Fraser AG, Hacohen N, Hahn WC, Jackson AL, Kiger A, Linsley PS, Lum L, Ma Y, Mathey-Prévôt B, Root DE, Sabatini DM, Taipale J, Perrimon N, Bernards R. Echeverri CJ, et al. Among authors: linsley ps. Nat Methods. 2006 Oct;3(10):777-9. doi: 10.1038/nmeth1006-777. Nat Methods. 2006. PMID: 16990807
Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions.
Bartz SR, Zhang Z, Burchard J, Imakura M, Martin M, Palmieri A, Needham R, Guo J, Gordon M, Chung N, Warrener P, Jackson AL, Carleton M, Oatley M, Locco L, Santini F, Smith T, Kunapuli P, Ferrer M, Strulovici B, Friend SH, Linsley PS. Bartz SR, et al. Among authors: linsley ps. Mol Cell Biol. 2006 Dec;26(24):9377-86. doi: 10.1128/MCB.01229-06. Epub 2006 Sep 25. Mol Cell Biol. 2006. PMID: 17000754 Free PMC article.
309 results