Roh EJ - Search Results

1

P2Y1 antagonists: combining receptor-based modeling and QSAR for a quantitative prediction of the biological activity based on consensus scoring.

Costanzi S, Tikhonova IG, Ohno M, Roh EJ, Joshi BV, Colson AO, Houston D, Maddileti S, Harden TK, Jacobson KA. Costanzi S, et al. Among authors: roh ej. J Med Chem. 2007 Jul 12;50(14):3229-41. doi: 10.1021/jm0700971. Epub 2007 Jun 12. J Med Chem. 2007. PMID: 17564423

2

Synthesis, biological activity and receptor-based 3-D QSAR study of 3'-N-substituted-3'-N-debenzoylpaclitaxel analogues.

Roh EJ, Kim D, Choi JY, Lee BS, Lee CO, Song CE. Roh EJ, et al. Bioorg Med Chem. 2002 Oct;10(10):3135-43. doi: 10.1016/s0968-0896(02)00217-1. Bioorg Med Chem. 2002. PMID: 12150858

3

MRS2500 [2-iodo-N6-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate], a potent, selective, and stable antagonist of the platelet P2Y1 receptor with strong antithrombotic activity in mice.

Hechler B, Nonne C, Roh EJ, Cattaneo M, Cazenave JP, Lanza F, Jacobson KA, Gachet C. Hechler B, et al. Among authors: roh ej. J Pharmacol Exp Ther. 2006 Feb;316(2):556-63. doi: 10.1124/jpet.105.094037. Epub 2005 Oct 19. J Pharmacol Exp Ther. 2006. PMID: 16236815 Free PMC article.

4

Action of nucleosides and nucleotides at 7 transmembrane-spanning receptors.

Jacobson KA, Costanzi S, Kim SK, Roh E, Joshi BV, Tchilibon S, Duong HT, Gao ZG. Jacobson KA, et al. Nucleosides Nucleotides Nucleic Acids. 2006;25(12):1425-36. doi: 10.1080/15257770600919027. Nucleosides Nucleotides Nucleic Acids. 2006. PMID: 17067963 Free PMC article. Review.

5

Structure-activity relationships of 1,4-dihydropyridines that act as enhancers of the vanilloid receptor 1 (TRPV1).

Roh EJ, Keller JM, Olah Z, Iadarola MJ, Jacobson KA. Roh EJ, et al. Bioorg Med Chem. 2008 Oct 15;16(20):9349-58. doi: 10.1016/j.bmc.2008.08.048. Epub 2008 Aug 26. Bioorg Med Chem. 2008. PMID: 18809334 Free PMC article.

6

Structure-based optimization and biological evaluation of trisubstituted pyrazole as a core structure of potent ROS1 kinase inhibitors.

Park BS, Al-Sanea MM, Abdelazem AZ, Park HM, Roh EJ, Park HM, Yoo KH, Sim T, Tae JS, Lee SH. Park BS, et al. Among authors: roh ej. Bioorg Med Chem. 2014 Aug 1;22(15):3871-8. doi: 10.1016/j.bmc.2014.06.020. Epub 2014 Jun 18. Bioorg Med Chem. 2014. PMID: 24997577

7

Synthesis and structure-activity relationships of tri-substituted thiazoles as RAGE antagonists for the treatment of Alzheimer's disease.

Lee YS, Kim H, Kim YH, Roh EJ, Han H, Shin KJ. Lee YS, et al. Among authors: roh ej. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7555-61. doi: 10.1016/j.bmcl.2012.10.022. Epub 2012 Oct 13. Bioorg Med Chem Lett. 2012. PMID: 23140885

8

Novel quinazoline-urea analogues as modulators for Aβ-induced mitochondrial dysfunction: design, synthesis, and molecular docking study.

Elkamhawy A, Lee J, Park BG, Park I, Pae AN, Roh EJ. Elkamhawy A, et al. Among authors: roh ej. Eur J Med Chem. 2014 Sep 12;84:466-75. doi: 10.1016/j.ejmech.2014.07.027. Epub 2014 Jul 9. Eur J Med Chem. 2014. PMID: 25050879

9

Targeting EGFR/HER2 tyrosine kinases with a new potent series of 6-substituted 4-anilinoquinazoline hybrids: Design, synthesis, kinase assay, cell-based assay, and molecular docking.

Elkamhawy A, Farag AK, Viswanath AN, Bedair TM, Leem DG, Lee KT, Pae AN, Roh EJ. Elkamhawy A, et al. Among authors: roh ej. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5147-54. doi: 10.1016/j.bmcl.2015.10.003. Epub 2015 Oct 9. Bioorg Med Chem Lett. 2015. PMID: 26475520

10

Radiolabeling of paclitaxel with electrophilic 123I.

Roh EJ, Park YH, Song CE, Oh SJ, Choe YS, Kim BT, Chi DY, Kim D. Roh EJ, et al. Bioorg Med Chem. 2000 Jan;8(1):65-8. doi: 10.1016/s0968-0896(99)00255-2. Bioorg Med Chem. 2000. PMID: 10968265

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