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Page 1
Himbacine derived thrombin receptor (PAR-1) antagonists: SAR of the pyridine ring.
Xia Y, Chackalamannil S, Clasby M, Doller D, Eagen K, Greenlee WJ, Tsai H, Agans-Fantuzzi J, Ahn HS, Boykow GC, Hsieh Y, Lunn CA, Chintala M. Xia Y, et al. Among authors: doller d. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4509-13. doi: 10.1016/j.bmcl.2007.06.002. Epub 2007 Jun 15. Bioorg Med Chem Lett. 2007. PMID: 17574850
Potent non-peptide thrombin receptor antagonists.
Chackalamannil S, Ahn HS, Xia Y, Doller D, Foster C. Chackalamannil S, et al. Among authors: doller d. Curr Med Chem Cardiovasc Hematol Agents. 2003 Mar;1(1):37-45. doi: 10.2174/1568016033356706. Curr Med Chem Cardiovasc Hematol Agents. 2003. PMID: 15317289 Review.
Metabolism-based identification of a potent thrombin receptor antagonist.
Clasby MC, Chackalamannil S, Czarniecki M, Doller D, Eagen K, Greenlee W, Kao G, Lin Y, Tsai H, Xia Y, Ahn HS, Agans-Fantuzzi J, Boykow G, Chintala M, Foster C, Smith-Torhan A, Alton K, Bryant M, Hsieh Y, Lau J, Palamanda J. Clasby MC, et al. Among authors: doller d. J Med Chem. 2007 Jan 11;50(1):129-38. doi: 10.1021/jm061043e. J Med Chem. 2007. PMID: 17201416
Himbacine derived thrombin receptor antagonists: discovery of a new tricyclic core.
Clasby MC, Chackalamannil S, Czarniecki M, Doller D, Eagen K, Greenlee WJ, Lin Y, Tagat JR, Tsai H, Xia Y, Ahn HS, Agans-Fantuzzi J, Boykow G, Chintala M, Hsieh Y, McPhail AT. Clasby MC, et al. Among authors: doller d. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3647-51. doi: 10.1016/j.bmcl.2007.04.061. Epub 2007 Apr 25. Bioorg Med Chem Lett. 2007. PMID: 17490877
Potent, low molecular weight thrombin receptor antagonists.
Chackalamannil S, Doller D, Eagen K, Czarniecki M, Ahn HS, Foster CJ, Boykow G. Chackalamannil S, et al. Among authors: doller d. Bioorg Med Chem Lett. 2001 Nov 5;11(21):2851-3. doi: 10.1016/s0960-894x(01)00555-8. Bioorg Med Chem Lett. 2001. PMID: 11597414
54 results