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The PIGRET assay, a method for measuring Pig-a gene mutation in reticulocytes, is reliable as a short-term in vivo genotoxicity test: Summary of the MMS/JEMS-collaborative study across 16 laboratories using 24 chemicals.
Kimoto T, Horibata K, Miura D, Chikura S, Okada Y, Ukai A, Itoh S, Nakayama S, Sanada H, Koyama N, Muto S, Uno Y, Yamamoto M, Suzuki Y, Fukuda T, Goto K, Wada K, Kyoya T, Shigano M, Takasawa H, Hamada S, Adachi H, Uematsu Y, Tsutsumi E, Hori H, Kikuzuki R, Ogiwara Y, Yoshida I, Maeda A, Narumi K, Fujiishi Y, Morita T, Yamada M, Honma M. Kimoto T, et al. Among authors: takasawa h. Mutat Res Genet Toxicol Environ Mutagen. 2016 Nov 15;811:3-15. doi: 10.1016/j.mrgentox.2016.10.003. Epub 2016 Oct 21. Mutat Res Genet Toxicol Environ Mutagen. 2016. PMID: 27931811 Free article.
Measuring reproducibility of dose response data for the Pig-a assay using covariate benchmark dose analysis.
Johnson GE, Yamamoto M, Suzuki Y, Adachi H, Kyoya T, Takasawa H, Horibata K, Tsutsumi E, Wada K, Kikuzuki R, Yoshida I, Kimoto T, Maeda A, Narumi K. Johnson GE, et al. Among authors: takasawa h. Mutat Res Genet Toxicol Environ Mutagen. 2016 Nov 15;811:135-139. doi: 10.1016/j.mrgentox.2016.04.004. Epub 2016 Apr 16. Mutat Res Genet Toxicol Environ Mutagen. 2016. PMID: 27931807
Evaluation of the sensitivity and specificity of in vivo erythrocyte micronucleus and transgenic rodent gene mutation tests to detect rodent carcinogens.
Morita T, Hamada S, Masumura K, Wakata A, Maniwa J, Takasawa H, Yasunaga K, Hashizume T, Honma M. Morita T, et al. Among authors: takasawa h. Mutat Res Genet Toxicol Environ Mutagen. 2016 May;802:1-29. doi: 10.1016/j.mrgentox.2016.03.008. Epub 2016 Mar 21. Mutat Res Genet Toxicol Environ Mutagen. 2016. PMID: 27169373 Free article.
40 results