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Tyrosyl-DNA phosphodiesterase as a target for anticancer therapy.
Dexheimer TS, Antony S, Marchand C, Pommier Y. Dexheimer TS, et al. Among authors: antony s. Anticancer Agents Med Chem. 2008 May;8(4):381-9. doi: 10.2174/187152008784220357. Anticancer Agents Med Chem. 2008. PMID: 18473723 Free PMC article. Review.
Bisindenoisoquinoline bis-1,3-{(5,6-dihydro-5,11-diketo-11H-indeno[1,2-c]isoquinoline)-6-propylamino}propane bis(trifluoroacetate) (NSC 727357), a DNA intercalator and topoisomerase inhibitor with antitumor activity.
Antony S, Agama KK, Miao ZH, Hollingshead M, Holbeck SL, Wright MH, Varticovski L, Nagarajan M, Morrell A, Cushman M, Pommier Y. Antony S, et al. Mol Pharmacol. 2006 Sep;70(3):1109-20. doi: 10.1124/mol.106.024372. Epub 2006 Jun 23. Mol Pharmacol. 2006. PMID: 16798938
320 results