Bjornsti MA - Search Results

1

Antitumour drugs impede DNA uncoiling by topoisomerase I.

Koster DA, Palle K, Bot ES, Bjornsti MA, Dekker NH. Koster DA, et al. Among authors: bjornsti ma. Nature. 2007 Jul 12;448(7150):213-7. doi: 10.1038/nature05938. Epub 2007 Jun 24. Nature. 2007. PMID: 17589503

2

Cellular strategies for regulating DNA supercoiling: a single-molecule perspective.

Koster DA, Crut A, Shuman S, Bjornsti MA, Dekker NH. Koster DA, et al. Among authors: bjornsti ma. Cell. 2010 Aug 20;142(4):519-30. doi: 10.1016/j.cell.2010.08.001. Cell. 2010. PMID: 20723754 Free PMC article. Review.

3

Alterations in linker flexibility suppress DNA topoisomerase I mutant-induced cell lethality.

Losasso C, Cretaio E, Palle K, Pattarello L, Bjornsti MA, Benedetti P. Losasso C, et al. Among authors: bjornsti ma. J Biol Chem. 2007 Mar 30;282(13):9855-9864. doi: 10.1074/jbc.M608200200. Epub 2007 Feb 2. J Biol Chem. 2007. PMID: 17276985 Free article.

4

Inhibition of topoisomerase I cleavage activity by thiol-reactive compounds: importance of vicinal cysteines 504 and 505.

Montaudon D, Palle K, Rivory LP, Robert J, Douat-Casassus C, Quideau S, Bjornsti MA, Pourquier P. Montaudon D, et al. Among authors: bjornsti ma. J Biol Chem. 2007 May 11;282(19):14403-12. doi: 10.1074/jbc.M611673200. Epub 2007 Mar 12. J Biol Chem. 2007. PMID: 17355975 Free article.

5

Disulfide cross-links reveal conserved features of DNA topoisomerase I architecture and a role for the N terminus in clamp closure.

Palle K, Pattarello L, van der Merwe M, Losasso C, Benedetti P, Bjornsti MA. Palle K, et al. Among authors: bjornsti ma. J Biol Chem. 2008 Oct 10;283(41):27767-27775. doi: 10.1074/jbc.M804826200. Epub 2008 Aug 8. J Biol Chem. 2008. PMID: 18693244 Free PMC article.

6

Platinated DNA adducts enhance poisoning of DNA topoisomerase I by camptothecin.

van Waardenburg RC, de Jong LA, van Eijndhoven MA, Verseyden C, Pluim D, Jansen LE, Bjornsti MA, Schellens JH. van Waardenburg RC, et al. Among authors: bjornsti ma. J Biol Chem. 2004 Dec 24;279(52):54502-9. doi: 10.1074/jbc.M410103200. Epub 2004 Oct 6. J Biol Chem. 2004. PMID: 15471886 Free article.

7

Homologous recombination is a highly conserved determinant of the synergistic cytotoxicity between cisplatin and DNA topoisomerase I poisons.

van Waardenburg RC, de Jong LA, van Delft F, van Eijndhoven MA, Bohlander M, Bjornsti MA, Brouwer J, Schellens JH. van Waardenburg RC, et al. Among authors: bjornsti ma. Mol Cancer Ther. 2004 Apr;3(4):393-402. Mol Cancer Ther. 2004. PMID: 15078982

8

Yeast as a model organism for studying the actions of DNA topoisomerase-targeted drugs.

Reid RJ, Benedetti P, Bjornsti MA. Reid RJ, et al. Among authors: bjornsti ma. Biochim Biophys Acta. 1998 Oct 1;1400(1-3):289-300. doi: 10.1016/s0167-4781(98)00142-0. Biochim Biophys Acta. 1998. PMID: 9748633 Review.

9

Mechanisms of DNA topoisomerase I-induced cell killing in the yeast Saccharomyces cerevisiae.

Fiorani P, Bjornsti MA. Fiorani P, et al. Among authors: bjornsti ma. Ann N Y Acad Sci. 2000;922:65-75. doi: 10.1111/j.1749-6632.2000.tb07026.x. Ann N Y Acad Sci. 2000. PMID: 11193926 Review.

10

Substitution of conserved residues within the active site alters the cleavage religation equilibrium of DNA topoisomerase I.

Colley WC, van der Merwe M, Vance JR, Burgin AB Jr, Bjornsti MA. Colley WC, et al. Among authors: bjornsti ma. J Biol Chem. 2004 Dec 24;279(52):54069-78. doi: 10.1074/jbc.M409764200. Epub 2004 Oct 15. J Biol Chem. 2004. PMID: 15489506 Free article.

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