Brandt R - Search Results

1

A Caenorhabditis elegans model of tau hyperphosphorylation: induction of developmental defects by transgenic overexpression of Alzheimer's disease-like modified tau.

Brandt R, Gergou A, Wacker I, Fath T, Hutter H. Brandt R, et al. Neurobiol Aging. 2009 Jan;30(1):22-33. doi: 10.1016/j.neurobiolaging.2007.05.011. Epub 2007 Jun 22. Neurobiol Aging. 2009. PMID: 17590239

2

Herpes simplex virus-mediated expression of the axonal protein tau in human model neurons (NT2-N cells).

Fath T, Eidenmüller J, Maas T, Brandt R. Fath T, et al. Among authors: brandt r. Microsc Res Tech. 2000 Jan 15;48(2):85-96. doi: 10.1002/(SICI)1097-0029(20000115)48:2<85::AID-JEMT4>3.0.CO;2-O. Microsc Res Tech. 2000. PMID: 10649509

3

Structural and functional implications of tau hyperphosphorylation: information from phosphorylation-mimicking mutated tau proteins.

Eidenmüller J, Fath T, Hellwig A, Reed J, Sontag E, Brandt R. Eidenmüller J, et al. Among authors: brandt r. Biochemistry. 2000 Oct 31;39(43):13166-75. doi: 10.1021/bi001290z. Biochemistry. 2000. PMID: 11052669

4

Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein.

Eidenmüller J, Fath T, Maas T, Pool M, Sontag E, Brandt R. Eidenmüller J, et al. Among authors: brandt r. Biochem J. 2001 Aug 1;357(Pt 3):759-67. doi: 10.1042/0264-6021:3570759. Biochem J. 2001. PMID: 11463346 Free PMC article.

5

Cytoskeletal mechanisms of neuronal degeneration.

Brandt R. Brandt R. Cell Tissue Res. 2001 Aug;305(2):255-65. doi: 10.1007/s004410000334. Cell Tissue Res. 2001. PMID: 11545263 Review.

6

Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease.

Fath T, Eidenmüller J, Brandt R. Fath T, et al. Among authors: brandt r. J Neurosci. 2002 Nov 15;22(22):9733-41. doi: 10.1523/JNEUROSCI.22-22-09733.2002. J Neurosci. 2002. PMID: 12427828 Free PMC article.

7

Functions and malfunctions of the tau proteins.

Shahani N, Brandt R. Shahani N, et al. Among authors: brandt r. Cell Mol Life Sci. 2002 Oct;59(10):1668-80. doi: 10.1007/pl00012495. Cell Mol Life Sci. 2002. PMID: 12475178 Free PMC article. Review.

8

Tau alteration and neuronal degeneration in tauopathies: mechanisms and models.

Brandt R, Hundelt M, Shahani N. Brandt R, et al. Biochim Biophys Acta. 2005 Jan 3;1739(2-3):331-54. doi: 10.1016/j.bbadis.2004.06.018. Biochim Biophys Acta. 2005. PMID: 15615650 Free article. Review.

9

Functional interactions of tau and their relevance for Alzheimer's disease.

Brandt R, Leschik J. Brandt R, et al. Curr Alzheimer Res. 2004 Nov;1(4):255-69. doi: 10.2174/1567205043332054. Curr Alzheimer Res. 2004. PMID: 15975055 Review.

10

Tau aggregation and progressive neuronal degeneration in the absence of changes in spine density and morphology after targeted expression of Alzheimer's disease-relevant tau constructs in organotypic hippocampal slices.

Shahani N, Subramaniam S, Wolf T, Tackenberg C, Brandt R. Shahani N, et al. Among authors: brandt r. J Neurosci. 2006 May 31;26(22):6103-14. doi: 10.1523/JNEUROSCI.4245-05.2006. J Neurosci. 2006. PMID: 16738255 Free PMC article.

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