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Peripheral administration of the N-terminal pro-opiomelanocortin fragment 1-28 to Pomc-/- mice reduces food intake and weight but does not affect adrenal growth or corticosterone production.
Coll AP, Fassnacht M, Klammer S, Hahner S, Schulte DM, Piper S, Tung YC, Challis BG, Weinstein Y, Allolio B, O'Rahilly S, Beuschlein F. Coll AP, et al. J Endocrinol. 2006 Aug;190(2):515-25. doi: 10.1677/joe.1.06749. J Endocrinol. 2006. PMID: 16899584 Free PMC article.
The hormonal control of food intake.
Coll AP, Farooqi IS, O'Rahilly S. Coll AP, et al. Cell. 2007 Apr 20;129(2):251-62. doi: 10.1016/j.cell.2007.04.001. Cell. 2007. PMID: 17448988 Free PMC article. Review.
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase.
Gerken T, Girard CA, Tung YC, Webby CJ, Saudek V, Hewitson KS, Yeo GS, McDonough MA, Cunliffe S, McNeill LA, Galvanovskis J, Rorsman P, Robins P, Prieur X, Coll AP, Ma M, Jovanovic Z, Farooqi IS, Sedgwick B, Barroso I, Lindahl T, Ponting CP, Ashcroft FM, O'Rahilly S, Schofield CJ. Gerken T, et al. Science. 2007 Nov 30;318(5855):1469-72. doi: 10.1126/science.1151710. Epub 2007 Nov 8. Science. 2007. PMID: 17991826 Free PMC article.
SnapShot: the hormonal control of food intake.
Coll AP, Yeo GS, Farooqi IS, O'Rahilly S. Coll AP, et al. Cell. 2008 Oct 31;135(3):572.e1-2. doi: 10.1016/j.cell.2008.10.014. Cell. 2008. PMID: 18984167 Free article. No abstract available.
559 results