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A single 20 mg dose of the full D1 dopamine agonist dihydrexidine (DAR-0100) increases prefrontal perfusion in schizophrenia.
Mu Q, Johnson K, Morgan PS, Grenesko EL, Molnar CE, Anderson B, Nahas Z, Kozel FA, Kose S, Knable M, Fernandes P, Nichols DE, Mailman RB, George MS. Mu Q, et al. Among authors: johnson k. Schizophr Res. 2007 Aug;94(1-3):332-41. doi: 10.1016/j.schres.2007.03.033. Epub 2007 Jun 27. Schizophr Res. 2007. PMID: 17596915 Clinical Trial.
A single 20 mg dose of dihydrexidine (DAR-0100), a full dopamine D1 agonist, is safe and tolerated in patients with schizophrenia.
George MS, Molnar CE, Grenesko EL, Anderson B, Mu Q, Johnson K, Nahas Z, Knable M, Fernandes P, Juncos J, Huang X, Nichols DE, Mailman RB. George MS, et al. Among authors: johnson k. Schizophr Res. 2007 Jul;93(1-3):42-50. doi: 10.1016/j.schres.2007.03.011. Epub 2007 Apr 30. Schizophr Res. 2007. PMID: 17467956 Clinical Trial.
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