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411 results

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DNA-methylation of the homeodomain transcription factor PITX2 reliably predicts risk of distant disease recurrence in tamoxifen-treated, node-negative breast cancer patients--Technical and clinical validation in a multi-centre setting in collaboration with the European Organisation for Research and Treatment of Cancer (EORTC) PathoBiology group.
Maier S, Nimmrich I, Koenig T, Eppenberger-Castori S, Bohlmann I, Paradiso A, Spyratos F, Thomssen C, Mueller V, Nährig J, Schittulli F, Kates R, Lesche R, Schwope I, Kluth A, Marx A, Martens JW, Foekens JA, Schmitt M, Harbeck N; European Organisation for Research and Treatment of Cancer (EORTC) PathoBiology group. Maier S, et al. Among authors: foekens ja. Eur J Cancer. 2007 Jul;43(11):1679-86. doi: 10.1016/j.ejca.2007.04.025. Epub 2007 Jun 29. Eur J Cancer. 2007. PMID: 17601725
Multicenter study using paraffin-embedded tumor tissue testing PITX2 DNA methylation as a marker for outcome prediction in tamoxifen-treated, node-negative breast cancer patients.
Harbeck N, Nimmrich I, Hartmann A, Ross JS, Cufer T, Grützmann R, Kristiansen G, Paradiso A, Hartmann O, Margossian A, Martens J, Schwope I, Lukas A, Müller V, Milde-Langosch K, Nährig J, Foekens J, Maier S, Schmitt M, Lesche R. Harbeck N, et al. J Clin Oncol. 2008 Nov 1;26(31):5036-42. doi: 10.1200/JCO.2007.14.1697. Epub 2008 Aug 18. J Clin Oncol. 2008. PMID: 18711169
DNA hypermethylation of PITX2 is a marker of poor prognosis in untreated lymph node-negative hormone receptor-positive breast cancer patients.
Nimmrich I, Sieuwerts AM, Meijer-van Gelder ME, Schwope I, Bolt-de Vries J, Harbeck N, Koenig T, Hartmann O, Kluth A, Dietrich D, Magdolen V, Portengen H, Look MP, Klijn JG, Lesche R, Schmitt M, Maier S, Foekens JA, Martens JW. Nimmrich I, et al. Among authors: foekens ja. Breast Cancer Res Treat. 2008 Oct;111(3):429-37. doi: 10.1007/s10549-007-9800-8. Epub 2007 Oct 28. Breast Cancer Res Treat. 2008. PMID: 17965955
DNA methylation markers predict outcome in node-positive, estrogen receptor-positive breast cancer with adjuvant anthracycline-based chemotherapy.
Hartmann O, Spyratos F, Harbeck N, Dietrich D, Fassbender A, Schmitt M, Eppenberger-Castori S, Vuaroqueaux V, Lerebours F, Welzel K, Maier S, Plum A, Niemann S, Foekens JA, Lesche R, Martens JW. Hartmann O, et al. Among authors: foekens ja. Clin Cancer Res. 2009 Jan 1;15(1):315-23. doi: 10.1158/1078-0432.CCR-08-0166. Clin Cancer Res. 2009. PMID: 19118060 Clinical Trial.
CDO1 promoter methylation is a biomarker for outcome prediction of anthracycline treated, estrogen receptor-positive, lymph node-positive breast cancer patients.
Dietrich D, Krispin M, Dietrich J, Fassbender A, Lewin J, Harbeck N, Schmitt M, Eppenberger-Castori S, Vuaroqueaux V, Spyratos F, Foekens JA, Lesche R, Martens JW. Dietrich D, et al. Among authors: foekens ja. BMC Cancer. 2010 Jun 1;10:247. doi: 10.1186/1471-2407-10-247. BMC Cancer. 2010. PMID: 20515469 Free PMC article.
DNA methylation as a biomarker in breast cancer.
Martens JW, Margossian AL, Schmitt M, Foekens J, Harbeck N. Martens JW, et al. Future Oncol. 2009 Oct;5(8):1245-56. doi: 10.2217/fon.09.89. Future Oncol. 2009. PMID: 19852739 Review.
Association of DNA methylation of phosphoserine aminotransferase with response to endocrine therapy in patients with recurrent breast cancer.
Martens JW, Nimmrich I, Koenig T, Look MP, Harbeck N, Model F, Kluth A, Bolt-de Vries J, Sieuwerts AM, Portengen H, Meijer-Van Gelder ME, Piepenbrock C, Olek A, Höfler H, Kiechle M, Klijn JG, Schmitt M, Maier S, Foekens JA. Martens JW, et al. Among authors: foekens ja. Cancer Res. 2005 May 15;65(10):4101-17. doi: 10.1158/0008-5472.CAN-05-0064. Cancer Res. 2005. PMID: 15899800
European Organisation for Research and Treatment of Cancer (EORTC) Pathobiology Group standard operating procedure for the preparation of human tumour tissue extracts suited for the quantitative analysis of tissue-associated biomarkers.
Schmitt M, Mengele K, Schueren E, Sweep FC, Foekens JA, Brünner N, Laabs J, Malik A, Harbeck N; European Organisation for Research and Treatment of Cancer Pathobiology Group. Schmitt M, et al. Among authors: foekens ja. Eur J Cancer. 2007 Mar;43(5):835-44. doi: 10.1016/j.ejca.2007.01.008. Epub 2007 Feb 23. Eur J Cancer. 2007. PMID: 17321128
Harmonisation of multi-centre real-time reverse-transcribed PCR results of a candidate prognostic marker in breast cancer: an EU-FP6 supported study of members of the EORTC - PathoBiology Group.
Span PN, Sieuwerts AM, Heuvel JJ, Spyratos F, Duffy MJ, Eppenberger-Castori S, Vacher S, O'Brien K, McKiernan E, Pierce A, Vuaroqueaux V, Foekens JA, Sweep FC, Martens JW. Span PN, et al. Among authors: foekens ja. Eur J Cancer. 2009 Jan;45(1):74-81. doi: 10.1016/j.ejca.2008.09.030. Epub 2008 Nov 12. Eur J Cancer. 2009. PMID: 19008094
411 results