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Respiratory syncytial virus fusion inhibitors. Part 6: an examination of the effect of structural variation of the benzimidazol-2-one heterocycle moiety.
Combrink KD, Gulgeze HB, Thuring JW, Yu KL, Civiello RL, Zhang Y, Pearce BC, Yin Z, Langley DR, Kadow KF, Cianci CW, Li Z, Clarke J, Genovesi EV, Medina I, Lamb L, Yang Z, Zadjura L, Krystal M, Meanwell NA. Combrink KD, et al. Among authors: krystal m. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4784-90. doi: 10.1016/j.bmcl.2007.06.065. Epub 2007 Jun 26. Bioorg Med Chem Lett. 2007. PMID: 17616396
Antiviral Properties of HIV-1 Capsid Inhibitor GSK878.
Wang C, Huang H, Mallon K, Valera L, Parcella K, Cockett MI, Kadow JF, Gillis EP, Krystal M, Fridell RA. Wang C, et al. Among authors: krystal m. Antimicrob Agents Chemother. 2023 May 17;67(5):e0169422. doi: 10.1128/aac.01694-22. Epub 2023 Apr 11. Antimicrob Agents Chemother. 2023. PMID: 37039636 Free PMC article.
Molecular mechanism underlying the action of a novel fusion inhibitor of influenza A virus.
Luo G, Torri A, Harte WE, Danetz S, Cianci C, Tiley L, Day S, Mullaney D, Yu KL, Ouellet C, Dextraze P, Meanwell N, Colonno R, Krystal M. Luo G, et al. Among authors: krystal m. J Virol. 1997 May;71(5):4062-70. doi: 10.1128/JVI.71.5.4062-4070.1997. J Virol. 1997. PMID: 9094684 Free PMC article.
Recently, we identified and characterized BMY-27709 as an inhibitor of the H1 and H2 subtypes of influenza A virus that specifically inhibits the HA function necessary for virus-cell membrane fusion (G.-X. Luo, R. Colonno, and M. Krystal, Virology 226:66-76, 1996). …
Recently, we identified and characterized BMY-27709 as an inhibitor of the H1 and H2 subtypes of influenza A virus that specifically inhibit …
Novel quinolizidine salicylamide influenza fusion inhibitors.
Yu KL, Ruediger E, Luo G, Cianci C, Danetz S, Tiley L, Trehan AK, Monkovic I, Pearce B, Martel A, Krystal M, Meanwell NA. Yu KL, et al. Among authors: krystal m. Bioorg Med Chem Lett. 1999 Aug 2;9(15):2177-80. doi: 10.1016/s0960-894x(99)00361-3. Bioorg Med Chem Lett. 1999. PMID: 10465540
Salicylamide inhibitors of influenza virus fusion.
Combrink KD, Gulgeze HB, Yu KL, Pearce BC, Trehan AK, Wei J, Deshpande M, Krystal M, Torri A, Luo G, Cianci C, Danetz S, Tiley L, Meanwell NA. Combrink KD, et al. Among authors: krystal m. Bioorg Med Chem Lett. 2000 Aug 7;10(15):1649-52. doi: 10.1016/s0960-894x(00)00335-8. Bioorg Med Chem Lett. 2000. PMID: 10937716
145 results