Barral K - Search Results

1

In vitro suppression of K65R reverse transcriptase-mediated tenofovir- and adefovir-5'-diphosphate resistance conferred by the boranophosphonate derivatives.

Frangeul A, Barral K, Alvarez K, Canard B. Frangeul A, et al. Among authors: barral k. Antimicrob Agents Chemother. 2007 Sep;51(9):3162-7. doi: 10.1128/AAC.00145-07. Epub 2007 Jul 9. Antimicrob Agents Chemother. 2007. PMID: 17620380 Free PMC article.

2

Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein-Protein Interaction: A Semi-Automated "Hit Identification-to-Optimization" Approach.

Hoffer L, Garcia M, Leblanc R, Feracci M, Betzi S, Ben Yaala K, Daulat AM, Zimmermann P, Roche P, Barral K, Morelli X. Hoffer L, et al. Among authors: barral k. J Med Chem. 2023 Apr 13;66(7):4633-4658. doi: 10.1021/acs.jmedchem.2c01569. Epub 2023 Mar 20. J Med Chem. 2023. PMID: 36939673

3

Borano-nucleotides: new analogues to circumvent HIV-1 RT-mediated nucleoside drug-resistance.

Alvarez K, Deval J, Selmi B, Barral K, Boretto J, Guerreiro C, Mulard L, Sarfati R, Canard B. Alvarez K, et al. Among authors: barral k. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):419-21. doi: 10.1081/NCN-200059951. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16247962

4

Synthesis, in vitro antiviral evaluation, and stability studies of novel alpha-borano-nucleotide analogues of 9-[2-(phosphonomethoxy)ethyl]adenine and (R)-9-[2-(phosphonomethoxy)propyl]adenine.

Barral K, Priet S, Sire J, Neyts J, Balzarini J, Canard B, Alvarez K. Barral K, et al. J Med Chem. 2006 Dec 28;49(26):7799-806. doi: 10.1021/jm060030y. J Med Chem. 2006. PMID: 17181162

5

Gln151 of HIV-1 reverse transcriptase acts as a steric gate towards clinically relevant acyclic phosphonate nucleotide analogues.

Frangeul A, Bussetta C, Deval J, Barral K, Alvarez K, Canard B. Frangeul A, et al. Among authors: barral k. Antivir Ther. 2008;13(1):115-24. Antivir Ther. 2008. PMID: 18389906

6

Acyclic phosphonate nucleotides and human adenylate kinases: impact of a borano group on alpha-P position.

Topalis D, Alvarez K, Barral K, Munier-Lehmann H, Schneider B, Véron M, Guerreiro C, Mulard L, El-Amri C, Canard B, Deville-Bonne D. Topalis D, et al. Among authors: barral k. Nucleosides Nucleotides Nucleic Acids. 2008 Apr;27(4):319-31. doi: 10.1080/15257770801941952. Nucleosides Nucleotides Nucleic Acids. 2008. PMID: 18404568

7

Synthesis and antiviral activity of boranophosphonate isosteres of AZT and d4T monophosphates.

Barral K, Priet S, De Michelis C, Sire J, Neyts J, Balzarini J, Canard B, Alvarez K. Barral K, et al. Eur J Med Chem. 2010 Feb;45(2):849-56. doi: 10.1016/j.ejmech.2009.11.012. Epub 2009 Nov 12. Eur J Med Chem. 2010. PMID: 19969396

8

Acyclic nucleoside thiophosphonates as potent inhibitors of HIV and HBV replication.

Barral K, Weck C, Payrot N, Roux L, Durafour C, Zoulim F, Neyts J, Balzarini J, Canard B, Priet S, Alvarez K. Barral K, et al. Eur J Med Chem. 2011 Sep;46(9):4281-8. doi: 10.1016/j.ejmech.2011.06.034. Epub 2011 Jul 1. Eur J Med Chem. 2011. PMID: 21803462 Free PMC article.

9

Development of specific dengue virus 2'-O- and N7-methyltransferase assays for antiviral drug screening.

Barral K, Sallamand C, Petzold C, Coutard B, Collet A, Thillier Y, Zimmermann J, Vasseur JJ, Canard B, Rohayem J, Debart F, Decroly E. Barral K, et al. Antiviral Res. 2013 Sep;99(3):292-300. doi: 10.1016/j.antiviral.2013.06.001. Epub 2013 Jun 12. Antiviral Res. 2013. PMID: 23769894

10

Novel 2-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,3,4-oxadiazole and 3-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,2,4-oxadiazole derivatives as dengue virus inhibitors targeting NS5 polymerase.

Benmansour F, Eydoux C, Querat G, de Lamballerie X, Canard B, Alvarez K, Guillemot JC, Barral K. Benmansour F, et al. Among authors: barral k. Eur J Med Chem. 2016 Feb 15;109:146-56. doi: 10.1016/j.ejmech.2015.12.046. Epub 2015 Dec 29. Eur J Med Chem. 2016. PMID: 26774922

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