Grauslund M - Search Results

1

A mouse model for studying the interaction of bisdioxopiperazines with topoisomerase IIalpha in vivo.

Grauslund M, Thougaard AV, Füchtbauer A, Hofland KF, Hjorth PH, Jensen PB, Sehested M, Füchtbauer EM, Jensen LH. Grauslund M, et al. Mol Pharmacol. 2007 Oct;72(4):1003-14. doi: 10.1124/mol.107.036970. Epub 2007 Jul 10. Mol Pharmacol. 2007. PMID: 17622580

2

Characterisation of cytotoxicity and DNA damage induced by the topoisomerase II-directed bisdioxopiperazine anti-cancer agent ICRF-187 (dexrazoxane) in yeast and mammalian cells.

Jensen LH, Dejligbjerg M, Hansen LT, Grauslund M, Jensen PB, Sehested M. Jensen LH, et al. Among authors: grauslund m. BMC Pharmacol. 2004 Dec 2;4:31. doi: 10.1186/1471-2210-4-31. BMC Pharmacol. 2004. PMID: 15575955 Free PMC article.

3

Separation of bisdioxopiperazine- and vanadate resistance in topoisomerase II.

Sorensen TK, Grauslund M, Jensen PB, Sehested M, Jensen LH. Sorensen TK, et al. Among authors: grauslund m. Biochem Biophys Res Commun. 2005 Sep 2;334(3):853-60. doi: 10.1016/j.bbrc.2005.06.177. Biochem Biophys Res Commun. 2005. PMID: 16053917

4

Substituted purine analogues define a novel structural class of catalytic topoisomerase II inhibitors.

Jensen LH, Thougaard AV, Grauslund M, Søkilde B, Carstensen EV, Dvinge HK, Scudiero DA, Jensen PB, Shoemaker RH, Sehested M. Jensen LH, et al. Among authors: grauslund m. Cancer Res. 2005 Aug 15;65(16):7470-7. doi: 10.1158/0008-5472.CAN-05-0707. Cancer Res. 2005. PMID: 16103101

5

Quantitative proteomic analysis of post-translational modifications of human histones.

Beck HC, Nielsen EC, Matthiesen R, Jensen LH, Sehested M, Finn P, Grauslund M, Hansen AM, Jensen ON. Beck HC, et al. Among authors: grauslund m. Mol Cell Proteomics. 2006 Jul;5(7):1314-25. doi: 10.1074/mcp.M600007-MCP200. Epub 2006 Apr 20. Mol Cell Proteomics. 2006. PMID: 16627869 Free article.

6

A three-dimensional quantitative structure-activity relationship study of the inhibition of the ATPase activity and the strand passing catalytic activity of topoisomerase IIalpha by substituted purine analogs.

Jensen LH, Liang H, Shoemaker R, Grauslund M, Sehested M, Hasinoff BB. Jensen LH, et al. Among authors: grauslund m. Mol Pharmacol. 2006 Nov;70(5):1503-13. doi: 10.1124/mol.106.026856. Epub 2006 Jul 31. Mol Pharmacol. 2006. PMID: 16880287

7

Identification of predictive biomarkers for the histone deacetylase inhibitor belinostat in a panel of human cancer cell lines.

Dejligbjerg M, Grauslund M, Christensen IJ, Tjørnelund J, Buhl Jensen P, Sehested M. Dejligbjerg M, et al. Among authors: grauslund m. Cancer Biomark. 2008;4(2):101-9. doi: 10.3233/cbm-2008-4206. Cancer Biomark. 2008. PMID: 18503161

8

Differential effects of class I isoform histone deacetylase depletion and enzymatic inhibition by belinostat or valproic acid in HeLa cells.

Dejligbjerg M, Grauslund M, Litman T, Collins L, Qian X, Jeffers M, Lichenstein H, Jensen PB, Sehested M. Dejligbjerg M, et al. Among authors: grauslund m. Mol Cancer. 2008 Sep 12;7:70. doi: 10.1186/1476-4598-7-70. Mol Cancer. 2008. PMID: 18789133 Free PMC article.

9

Evaluation of the topoisomerase II-inactive bisdioxopiperazine ICRF-161 as a protectant against doxorubicin-induced cardiomyopathy.

Martin E, Thougaard AV, Grauslund M, Jensen PB, Bjorkling F, Hasinoff BB, Tjørnelund J, Sehested M, Jensen LH. Martin E, et al. Among authors: grauslund m. Toxicology. 2009 Jan 8;255(1-2):72-9. doi: 10.1016/j.tox.2008.10.011. Epub 2008 Oct 25. Toxicology. 2009. PMID: 19010377

10

A murine experimental anthracycline extravasation model: pathology and study of the involvement of topoisomerase II alpha and iron in the mechanism of tissue damage.

Thougaard AV, Langer SW, Hainau B, Grauslund M, Juhl BR, Jensen PB, Sehested M. Thougaard AV, et al. Among authors: grauslund m. Toxicology. 2010 Feb 28;269(1):67-72. doi: 10.1016/j.tox.2010.01.007. Epub 2010 Jan 15. Toxicology. 2010. PMID: 20079798

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