Nielsen P - Search Results

1

LNA (locked nucleic acid) and analogs as triplex-forming oligonucleotides.

Højland T, Kumar S, Babu BR, Umemoto T, Albaek N, Sharma PK, Nielsen P, Wengel J. Højland T, et al. Among authors: nielsen p. Org Biomol Chem. 2007 Aug 7;5(15):2375-9. doi: 10.1039/b706101c. Epub 2007 Jun 22. Org Biomol Chem. 2007. PMID: 17637956

2

Incorporation of (R)- and (S)-3',4'-seco-thymidine into oligodeoxynucleotides: hybridization properties and enzymatic stability.

Nielsen P, Kirpekar F, Wengel J. Nielsen P, et al. Nucleic Acids Res. 1994 Mar 11;22(5):703-10. doi: 10.1093/nar/22.5.703. Nucleic Acids Res. 1994. PMID: 8139908 Free PMC article.

3

Synthesis and evaluation of oligodeoxynucleotides containing acyclic nucleosides: introduction of three novel analogues and a summary.

Nielsen P, Dreiøe LH, Wengel J. Nielsen P, et al. Bioorg Med Chem. 1995 Jan;3(1):19-28. doi: 10.1016/0968-0896(94)00143-q. Bioorg Med Chem. 1995. PMID: 8612043

4

Structural basis of cleavage by RNase H of hybrids of arabinonucleic acids and RNA.

Minasov G, Teplova M, Nielsen P, Wengel J, Egli M. Minasov G, et al. Among authors: nielsen p. Biochemistry. 2000 Apr 4;39(13):3525-32. doi: 10.1021/bi992792j. Biochemistry. 2000. PMID: 10736151

5

The Eight Stereoisomers of LNA (Locked Nucleic Acid): A Remarkable Family of Strong RNA Binding Molecules We acknowledge the Danish Natural Science Research Council, the Danish Technical Research Council, and Exiqon A/S for financial support. Ms Britta M. Dahl is thanked for oligonucleotide synthesis, Dr. Carl E. Olsen for MALDI-MS analysis, and Ms. Karen Jørgensen for recording CD spectra.

Rajwanshi VK, Håkansson AE, Sørensen MD, Pitsch S, Singh SK, Kumar R, Nielsen P, Wengel J. Rajwanshi VK, et al. Among authors: nielsen p. Angew Chem Int Ed Engl. 2000 May;39(9):1656-1659. doi: 10.1002/(sici)1521-3773(20000502)39:9<1656::aid-anie1656>3.0.co;2-q. Angew Chem Int Ed Engl. 2000. PMID: 10820467 No abstract available.

6

The solution structure of a DNA duplex containing a single 1-(2-O,3-C-ethylene-beta-D-arabinofuranosyl)thymidine nucleoside.

Jørgensen LB, Nielsen P, Wengel J, Jacobsen JP. Jørgensen LB, et al. Among authors: nielsen p. J Biomol Struct Dyn. 2000 Aug;18(1):45-57. doi: 10.1080/07391102.2000.10506646. J Biomol Struct Dyn. 2000. PMID: 11021651

7

Synthesis of conformationally restricted dinucleotides by ring-closing metathesis.

Sørensen AM, Nielsen P. Sørensen AM, et al. Among authors: nielsen p. Org Lett. 2000 Dec 28;2(26):4217-9. doi: 10.1021/ol0067639. Org Lett. 2000. PMID: 11150203

8

Incorporation of alpha- and beta-LNA (locked nucleic acid) monomers in oligodeoxynucleotides with polarity reversals.

Christensen NK, Dahl BM, Nielsen P. Christensen NK, et al. Among authors: nielsen p. Bioorg Med Chem Lett. 2001 Jul 9;11(13):1765-8. doi: 10.1016/s0960-894x(01)00298-0. Bioorg Med Chem Lett. 2001. PMID: 11425556

9

Synthesis of a bicyclic analogue of AZT restricted in an unusual O4'-endo conformation.

Sørensen MH, Nielsen C, Nielsen P. Sørensen MH, et al. Among authors: nielsen c, nielsen p. J Org Chem. 2001 Jul 13;66(14):4878-86. doi: 10.1021/jo010299j. J Org Chem. 2001. PMID: 11442420

10

Synthesis and evaluation of alpha-LNA.

Christensen NK, Dalskov JK, Nielsen P. Christensen NK, et al. Among authors: nielsen p. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):825-8. doi: 10.1081/NCN-100002438. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11563124

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