Prosser DE - Search Results

1

Single A326G mutation converts human CYP24A1 from 25-OH-D3-24-hydroxylase into -23-hydroxylase, generating 1alpha,25-(OH)2D3-26,23-lactone.

Prosser DE, Kaufmann M, O'Leary B, Byford V, Jones G. Prosser DE, et al. Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12673-8. doi: 10.1073/pnas.0702093104. Epub 2007 Jul 23. Proc Natl Acad Sci U S A. 2007. PMID: 17646648 Free PMC article.

2

Enzymes involved in the activation and inactivation of vitamin D.

Prosser DE, Jones G. Prosser DE, et al. Trends Biochem Sci. 2004 Dec;29(12):664-73. doi: 10.1016/j.tibs.2004.10.005. Trends Biochem Sci. 2004. PMID: 15544953 Review.

3

Generation of a homology model for the human cytochrome P450, CYP24A1, and the testing of putative substrate binding residues by site-directed mutagenesis and enzyme activity studies.

Masuda S, Prosser DE, Guo YD, Kaufmann M, Jones G. Masuda S, et al. Among authors: prosser de. Arch Biochem Biophys. 2007 Apr 15;460(2):177-91. doi: 10.1016/j.abb.2006.11.030. Epub 2006 Dec 13. Arch Biochem Biophys. 2007. PMID: 17224124

4

Bioengineering anabolic vitamin D-25-hydroxylase activity into the human vitamin D catabolic enzyme, cytochrome P450 CYP24A1, by a V391L mutation.

Kaufmann M, Prosser DE, Jones G. Kaufmann M, et al. Among authors: prosser de. J Biol Chem. 2011 Aug 19;286(33):28729-28737. doi: 10.1074/jbc.M111.236679. Epub 2011 Jun 22. J Biol Chem. 2011. PMID: 21697097 Free PMC article.

5

25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): its important role in the degradation of vitamin D.

Jones G, Prosser DE, Kaufmann M. Jones G, et al. Among authors: prosser de. Arch Biochem Biophys. 2012 Jul 1;523(1):9-18. doi: 10.1016/j.abb.2011.11.003. Epub 2011 Nov 12. Arch Biochem Biophys. 2012. PMID: 22100522 Review.

6

Structural motif-based homology modeling of CYP27A1 and site-directed mutational analyses affecting vitamin D hydroxylation.

Prosser DE, Guo Y, Jia Z, Jones G. Prosser DE, et al. Biophys J. 2006 May 15;90(10):3389-409. doi: 10.1529/biophysj.105.069369. Epub 2006 Feb 24. Biophys J. 2006. PMID: 16500955 Free PMC article.

7

Cytochrome P450-mediated metabolism of vitamin D.

Jones G, Prosser DE, Kaufmann M. Jones G, et al. Among authors: prosser de. J Lipid Res. 2014 Jan;55(1):13-31. doi: 10.1194/jlr.R031534. Epub 2013 Apr 6. J Lipid Res. 2014. PMID: 23564710 Free PMC article. Review.

8

Metabolism of a 20-methyl substituted series of vitamin D analogs by cultured human cells: apparent reduction of 23-hydroxylation of the side chain by the 20-methyl group.

Shankar VN, Byford V, Prosser DE, Schroeder NJ, Makin HL, Wiesinger H, Neef G, Steinmeyer A, Jones G. Shankar VN, et al. Among authors: prosser de. Biochem Pharmacol. 2001 Apr 1;61(7):893-902. doi: 10.1016/s0006-2952(01)00546-9. Biochem Pharmacol. 2001. PMID: 11274975

9

Mutations in CYP24A1 and idiopathic infantile hypercalcemia.

Schlingmann KP, Kaufmann M, Weber S, Irwin A, Goos C, John U, Misselwitz J, Klaus G, Kuwertz-Bröking E, Fehrenbach H, Wingen AM, Güran T, Hoenderop JG, Bindels RJ, Prosser DE, Jones G, Konrad M. Schlingmann KP, et al. Among authors: prosser de. N Engl J Med. 2011 Aug 4;365(5):410-21. doi: 10.1056/NEJMoa1103864. Epub 2011 Jun 15. N Engl J Med. 2011. PMID: 21675912 Free article.

10

Synthesis and CYP24A1 inhibitory activity of (E)-2-(2-substituted benzylidene)- and 2-(2-substituted benzyl)-6-methoxy-tetralones.

Aboraia AS, Makowski B, Bahja A, Prosser D, Brancale A, Jones G, Simons C. Aboraia AS, et al. Eur J Med Chem. 2010 Oct;45(10):4427-34. doi: 10.1016/j.ejmech.2010.07.001. Epub 2010 Jul 8. Eur J Med Chem. 2010. PMID: 20655626

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

12 results

Search Page

Filters