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High Skp2 expression characterizes high-risk neuroblastomas independent of MYCN status.
Westermann F, Henrich KO, Wei JS, Lutz W, Fischer M, König R, Wiedemeyer R, Ehemann V, Brors B, Ernestus K, Leuschner I, Benner A, Khan J, Schwab M. Westermann F, et al. Among authors: ehemann v. Clin Cancer Res. 2007 Aug 15;13(16):4695-703. doi: 10.1158/1078-0432.CCR-06-2818. Epub 2007 Jul 25. Clin Cancer Res. 2007. PMID: 17652624
Transcriptional repression of SKP2 is impaired in MYCN-amplified neuroblastoma.
Muth D, Ghazaryan S, Eckerle I, Beckett E, Pöhler C, Batzler J, Beisel C, Gogolin S, Fischer M, Henrich KO, Ehemann V, Gillespie P, Schwab M, Westermann F. Muth D, et al. Among authors: ehemann v. Cancer Res. 2010 May 1;70(9):3791-802. doi: 10.1158/0008-5472.CAN-09-1245. Epub 2010 Apr 27. Cancer Res. 2010. PMID: 20424123
MYCN/MYC-mediated drug resistance mechanisms in neuroblastoma.
Gogolin S, Dreidax D, Becker G, Ehemann V, Schwab M, Westermann F. Gogolin S, et al. Among authors: ehemann v. Int J Clin Pharmacol Ther. 2010 Jul;48(7):489-91. doi: 10.5414/cpp48489. Int J Clin Pharmacol Ther. 2010. PMID: 20557856 No abstract available.
MYCN-mediated overexpression of mitotic spindle regulatory genes and loss of p53-p21 function jointly support the survival of tetraploid neuroblastoma cells.
Gogolin S, Batra R, Harder N, Ehemann V, Paffhausen T, Diessl N, Sagulenko V, Benner A, Gade S, Nolte I, Rohr K, König R, Westermann F. Gogolin S, et al. Among authors: ehemann v. Cancer Lett. 2013 Apr 30;331(1):35-45. doi: 10.1016/j.canlet.2012.11.028. Epub 2012 Nov 24. Cancer Lett. 2013. PMID: 23186832
Low p14ARF expression in neuroblastoma cells is associated with repressed histone mark status, and enforced expression induces growth arrest and apoptosis.
Dreidax D, Gogolin S, Schroeder C, Muth D, Brueckner LM, Hess EM, Zapatka M, Theißen J, Fischer M, Ehemann V, Schwab M, Savelyeva L, Westermann F. Dreidax D, et al. Among authors: ehemann v. Hum Mol Genet. 2013 May 1;22(9):1735-45. doi: 10.1093/hmg/ddt020. Epub 2013 Jan 23. Hum Mol Genet. 2013. PMID: 23343716
p19-INK4d inhibits neuroblastoma cell growth, induces differentiation and is hypermethylated and downregulated in MYCN-amplified neuroblastomas.
Dreidax D, Bannert S, Henrich KO, Schröder C, Bender S, Oakes CC, Lindner S, Schulte JH, Duffy D, Schwarzl T, Saadati M, Ehemann V, Benner A, Pfister S, Fischer M, Westermann F. Dreidax D, et al. Among authors: ehemann v. Hum Mol Genet. 2014 Dec 20;23(25):6826-37. doi: 10.1093/hmg/ddu406. Epub 2014 Aug 7. Hum Mol Genet. 2014. PMID: 25104850
MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival.
Afanasyeva EA, Mestdagh P, Kumps C, Vandesompele J, Ehemann V, Theissen J, Fischer M, Zapatka M, Brors B, Savelyeva L, Sagulenko V, Speleman F, Schwab M, Westermann F. Afanasyeva EA, et al. Among authors: ehemann v. Cell Death Differ. 2011 Jun;18(6):974-84. doi: 10.1038/cdd.2010.164. Epub 2011 Jan 14. Cell Death Differ. 2011. PMID: 21233845 Free PMC article.
100 results