Johnson JF - Search Results

1

Genetic and pharmacologic evidence that Rac1 GTPase is involved in regulation of platelet secretion and aggregation.

Akbar H, Kim J, Funk K, Cancelas JA, Shang X, Chen L, Johnson JF, Williams DA, Zheng Y. Akbar H, et al. Among authors: johnson jf. J Thromb Haemost. 2007 Aug;5(8):1747-55. doi: 10.1111/j.1538-7836.2007.02646.x. J Thromb Haemost. 2007. PMID: 17663742 Free article.

2

Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton.

Kalfa TA, Pushkaran S, Mohandas N, Hartwig JH, Fowler VM, Johnson JF, Joiner CH, Williams DA, Zheng Y. Kalfa TA, et al. Among authors: johnson jf. Blood. 2006 Dec 1;108(12):3637-45. doi: 10.1182/blood-2006-03-005942. Epub 2006 Aug 1. Blood. 2006. PMID: 16882712 Free PMC article.

3

Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen.

Kalfa TA, Pushkaran S, Zhang X, Johnson JF, Pan D, Daria D, Geiger H, Cancelas JA, Williams DA, Zheng Y. Kalfa TA, et al. Among authors: johnson jf. Haematologica. 2010 Jan;95(1):27-35. doi: 10.3324/haematol.2009.006239. Haematologica. 2010. PMID: 20065081 Free PMC article.

4

Rac1 targeting suppresses p53 deficiency-mediated lymphomagenesis.

Bosco EE, Ni W, Wang L, Guo F, Johnson JF, Zheng Y. Bosco EE, et al. Among authors: johnson jf. Blood. 2010 Apr 22;115(16):3320-8. doi: 10.1182/blood-2009-02-202440. Epub 2010 Feb 23. Blood. 2010. PMID: 20179179 Free PMC article.

5

R-Ras and Rac GTPase cross-talk regulates hematopoietic progenitor cell migration, homing, and mobilization.

Shang X, Cancelas JA, Li L, Guo F, Liu W, Johnson JF, Ficker A, Daria D, Geiger H, Ratner N, Zheng Y. Shang X, et al. Among authors: johnson jf. J Biol Chem. 2011 Jul 8;286(27):24068-78. doi: 10.1074/jbc.M111.226951. Epub 2011 May 13. J Biol Chem. 2011. PMID: 21572048 Free PMC article.

6

Gene targeting implicates Cdc42 GTPase in GPVI and non-GPVI mediated platelet filopodia formation, secretion and aggregation.

Akbar H, Shang X, Perveen R, Berryman M, Funk K, Johnson JF, Tandon NN, Zheng Y. Akbar H, et al. Among authors: johnson jf. PLoS One. 2011;6(7):e22117. doi: 10.1371/journal.pone.0022117. Epub 2011 Jul 18. PLoS One. 2011. PMID: 21789221 Free PMC article.

7

Signaling and cytoskeletal requirements in erythroblast enucleation.

Konstantinidis DG, Pushkaran S, Johnson JF, Cancelas JA, Manganaris S, Harris CE, Williams DA, Zheng Y, Kalfa TA. Konstantinidis DG, et al. Among authors: johnson jf. Blood. 2012 Jun 21;119(25):6118-27. doi: 10.1182/blood-2011-09-379263. Epub 2012 Mar 28. Blood. 2012. PMID: 22461493 Free PMC article.

8

Pharmacologic targeting of Cdc42 GTPase by a small molecule Cdc42 activity-specific inhibitor prevents platelet activation and thrombosis.

Duan X, Perveen R, Dandamudi A, Adili R, Johnson J, Funk K, Berryman M, Davis AK, Holinstat M, Zheng Y, Akbar H. Duan X, et al. Sci Rep. 2021 Jun 23;11(1):13170. doi: 10.1038/s41598-021-92654-6. Sci Rep. 2021. PMID: 34162972 Free PMC article.

9

Inhibition of RHOA activity preserves the survival and hemostasis function of long-term cold-stored platelets.

Hegde S, Akbar H, Wellendorf AM, Nestheide S, Johnson JF, Zhao X, Setchell KD, Zheng Y, Cancelas JA. Hegde S, et al. Among authors: johnson jf. Blood. 2024 Oct 17;144(16):1732-1746. doi: 10.1182/blood.2023021453. Blood. 2024. PMID: 39088777

10

Cdc42 regulates bone modeling and remodeling in mice by modulating RANKL/M-CSF signaling and osteoclast polarization.

Ito Y, Teitelbaum SL, Zou W, Zheng Y, Johnson JF, Chappel J, Ross FP, Zhao H. Ito Y, et al. Among authors: johnson jf. J Clin Invest. 2010 Jun;120(6):1981-93. doi: 10.1172/JCI39650. Epub 2010 May 24. J Clin Invest. 2010. PMID: 20501942 Free PMC article.

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