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N-Acylthiadiazolines, a new class of liver X receptor agonists with selectivity for LXRbeta.
Molteni V, Li X, Nabakka J, Liang F, Wityak J, Koder A, Vargas L, Romeo R, Mitro N, Mak PA, Seidel HM, Haslam JA, Chow D, Tuntland T, Spalding TA, Brock A, Bradley M, Castrillo A, Tontonoz P, Saez E. Molteni V, et al. Among authors: mitro n. J Med Chem. 2007 Aug 23;50(17):4255-9. doi: 10.1021/jm070453f. Epub 2007 Aug 1. J Med Chem. 2007. PMID: 17665897
The nuclear receptor LXR is a glucose sensor.
Mitro N, Mak PA, Vargas L, Godio C, Hampton E, Molteni V, Kreusch A, Saez E. Mitro N, et al. Nature. 2007 Jan 11;445(7124):219-23. doi: 10.1038/nature05449. Epub 2006 Dec 24. Nature. 2007. PMID: 17187055
Dissection of the insulin-sensitizing effect of liver X receptor ligands.
Commerford SR, Vargas L, Dorfman SE, Mitro N, Rocheford EC, Mak PA, Li X, Kennedy P, Mullarkey TL, Saez E. Commerford SR, et al. Among authors: mitro n. Mol Endocrinol. 2007 Dec;21(12):3002-12. doi: 10.1210/me.2007-0156. Epub 2007 Aug 23. Mol Endocrinol. 2007. PMID: 17717069
Gene set enrichment in eQTL data identifies novel annotations and pathway regulators.
Wu C, Delano DL, Mitro N, Su SV, Janes J, McClurg P, Batalov S, Welch GL, Zhang J, Orth AP, Walker JR, Glynne RJ, Cooke MP, Takahashi JS, Shimomura K, Kohsaka A, Bass J, Saez E, Wiltshire T, Su AI. Wu C, et al. Among authors: mitro n. PLoS Genet. 2008 May 9;4(5):e1000070. doi: 10.1371/journal.pgen.1000070. PLoS Genet. 2008. PMID: 18464898 Free PMC article.
149 results