Epstein DM - Search Results

1

Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102.

Sennino B, Falcón BL, McCauley D, Le T, McCauley T, Kurz JC, Haskell A, Epstein DM, McDonald DM. Sennino B, et al. Among authors: epstein dm. Cancer Res. 2007 Aug 1;67(15):7358-67. doi: 10.1158/0008-5472.CAN-07-0293. Cancer Res. 2007. PMID: 17671206 Free PMC article.

2

Reduced VEGF production, angiogenesis, and vascular regrowth contribute to the antitumor properties of dual mTORC1/mTORC2 inhibitors.

Falcon BL, Barr S, Gokhale PC, Chou J, Fogarty J, Depeille P, Miglarese M, Epstein DM, McDonald DM. Falcon BL, et al. Among authors: epstein dm. Cancer Res. 2011 Mar 1;71(5):1573-83. doi: 10.1158/0008-5472.CAN-10-3126. Cancer Res. 2011. PMID: 21363918 Free PMC article.

3

Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation.

Fuxe J, Tabruyn S, Colton K, Zaid H, Adams A, Baluk P, Lashnits E, Morisada T, Le T, O'Brien S, Epstein DM, Koh GY, McDonald DM. Fuxe J, et al. Among authors: epstein dm. Am J Pathol. 2011 Jun;178(6):2897-909. doi: 10.1016/j.ajpath.2011.02.008. Epub 2011 May 6. Am J Pathol. 2011. PMID: 21550017 Free PMC article.

4

Anti-metastatic action of FAK inhibitor OXA-11 in combination with VEGFR-2 signaling blockade in pancreatic neuroendocrine tumors.

Moen I, Gebre M, Alonso-Camino V, Chen D, Epstein D, McDonald DM. Moen I, et al. Among authors: epstein d. Clin Exp Metastasis. 2015 Dec;32(8):799-817. doi: 10.1007/s10585-015-9752-z. Epub 2015 Oct 7. Clin Exp Metastasis. 2015. PMID: 26445848 Free PMC article.

5

Intraocular injection of an aptamer that binds PDGF-B: a potential treatment for proliferative retinopathies.

Akiyama H, Kachi S, Silva RL, Umeda N, Hackett SF, McCauley D, McCauley T, Zoltoski A, Epstein DM, Campochiaro PA. Akiyama H, et al. Among authors: epstein dm. J Cell Physiol. 2006 May;207(2):407-12. doi: 10.1002/jcp.20583. J Cell Physiol. 2006. PMID: 16419035

6

Direct in vitro selection of a 2'-O-methyl aptamer to VEGF.

Burmeister PE, Lewis SD, Silva RF, Preiss JR, Horwitz LR, Pendergrast PS, McCauley TG, Kurz JC, Epstein DM, Wilson C, Keefe AD. Burmeister PE, et al. Among authors: epstein dm. Chem Biol. 2005 Jan;12(1):25-33. doi: 10.1016/j.chembiol.2004.10.017. Chem Biol. 2005. PMID: 15664512

7

Pharmacologic and pharmacokinetic assessment of anti-TGFbeta2 aptamers in rabbit plasma and aqueous humor.

McCauley TG, Kurz JC, Merlino PG, Lewis SD, Gilbert M, Epstein DM, Marsh HN. McCauley TG, et al. Among authors: epstein dm. Pharm Res. 2006 Feb;23(2):303-11. doi: 10.1007/s11095-005-9305-2. Epub 2006 Jan 19. Pharm Res. 2006. PMID: 16411148

8

Feedback mechanisms promote cooperativity for small molecule inhibitors of epidermal and insulin-like growth factor receptors.

Buck E, Eyzaguirre A, Rosenfeld-Franklin M, Thomson S, Mulvihill M, Barr S, Brown E, O'Connor M, Yao Y, Pachter J, Miglarese M, Epstein D, Iwata KK, Haley JD, Gibson NW, Ji QS. Buck E, et al. Cancer Res. 2008 Oct 15;68(20):8322-32. doi: 10.1158/0008-5472.CAN-07-6720. Cancer Res. 2008. PMID: 18922904

9

AACR special conference on epithelial-mesenchymal transition and cancer progression and treatment.

Roussos ET, Keckesova Z, Haley JD, Epstein DM, Weinberg RA, Condeelis JS. Roussos ET, et al. Among authors: epstein dm. Cancer Res. 2010 Oct 1;70(19):7360-4. doi: 10.1158/0008-5472.CAN-10-1208. Epub 2010 Sep 7. Cancer Res. 2010. PMID: 20823151

10

Preclinical characterization of OSI-027, a potent and selective inhibitor of mTORC1 and mTORC2: distinct from rapamycin.

Bhagwat SV, Gokhale PC, Crew AP, Cooke A, Yao Y, Mantis C, Kahler J, Workman J, Bittner M, Dudkin L, Epstein DM, Gibson NW, Wild R, Arnold LD, Houghton PJ, Pachter JA. Bhagwat SV, et al. Among authors: epstein dm. Mol Cancer Ther. 2011 Aug;10(8):1394-406. doi: 10.1158/1535-7163.MCT-10-1099. Epub 2011 Jun 14. Mol Cancer Ther. 2011. PMID: 21673091

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