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A novel HSP90 inhibitor SL-145 suppresses metastatic triple-negative breast cancer without triggering the heat shock response.
Kim JY, Cho TM, Park JM, Park S, Park M, Nam KD, Ko D, Seo J, Kim S, Jung E, Farrand L, Nguyen CT, Hoang VH, Thanh La M, Ann J, Nam G, Park HJ, Lee J, Kim YJ, Seo JH. Kim JY, et al. Among authors: cho tm. Oncogene. 2022 Jun;41(23):3289-3297. doi: 10.1038/s41388-022-02269-y. Epub 2022 May 2. Oncogene. 2022. PMID: 35501463 Free PMC article.
Investigation of B,C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents.
Kim HS, Hoang VH, Hong M, Chul Kim K, Ann J, Nguyen CT, Seo JH, Choi H, Yong Kim J, Kim KW, Sub Byun W, Lee S, Lee S, Suh YG, Chen J, Park HJ, Cho TM, Kim JY, Seo JH, Lee J. Kim HS, et al. Among authors: cho tm. Bioorg Med Chem. 2019 Apr 1;27(7):1370-1381. doi: 10.1016/j.bmc.2019.02.040. Epub 2019 Feb 20. Bioorg Med Chem. 2019. PMID: 30827868
48 results