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PLCζ is the physiological trigger of the Ca2+ oscillations that induce embryogenesis in mammals but conception can occur in its absence.
Hachem A, Godwin J, Ruas M, Lee HC, Ferrer Buitrago M, Ardestani G, Bassett A, Fox S, Navarrete F, de Sutter P, Heindryckx B, Fissore R, Parrington J. Hachem A, et al. Among authors: godwin j. Development. 2017 Aug 15;144(16):2914-2924. doi: 10.1242/dev.150227. Epub 2017 Jul 10. Development. 2017. PMID: 28694258 Free PMC article.
The nuclear matrix protein CIZ1 facilitates localization of Xist RNA to the inactive X-chromosome territory.
Ridings-Figueroa R, Stewart ER, Nesterova TB, Coker H, Pintacuda G, Godwin J, Wilson R, Haslam A, Lilley F, Ruigrok R, Bageghni SA, Albadrani G, Mansfield W, Roulson JA, Brockdorff N, Ainscough JFX, Coverley D. Ridings-Figueroa R, et al. Among authors: godwin j. Genes Dev. 2017 May 1;31(9):876-888. doi: 10.1101/gad.295907.117. Epub 2017 May 25. Genes Dev. 2017. PMID: 28546514 Free PMC article.
Prion-like domains drive CIZ1 assembly formation at the inactive X chromosome.
Sofi S, Williamson L, Turvey GL, Scoynes C, Hirst C, Godwin J, Brockdorff N, Ainscough J, Coverley D. Sofi S, et al. Among authors: godwin j. J Cell Biol. 2022 Apr 4;221(4):e202103185. doi: 10.1083/jcb.202103185. Epub 2022 Mar 15. J Cell Biol. 2022. PMID: 35289833 Free PMC article.
729 results