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Page 1
Synthesis and characterization of nonsteroidal glucocorticoid receptor modulators for multiple myeloma.
Hudson AR, Roach SL, Higuchi RI, Phillips DP, Bissonnette RP, Lamph WW, Yen J, Li Y, Adams ME, Valdez LJ, Vassar A, Cuervo C, Kallel EA, Gharbaoui CJ, Mais DE, Miner JN, Marschke KB, Rungta D, Negro-Vilar A, Zhi L. Hudson AR, et al. Among authors: kallel ea. J Med Chem. 2007 Sep 20;50(19):4699-709. doi: 10.1021/jm070370z. Epub 2007 Aug 17. J Med Chem. 2007. PMID: 17705362
Potent, nonsteroidal selective androgen receptor modulators (SARMs) based on 8H-[1,4]oxazino[2,3-f]quinolin-8-ones.
Higuchi RI, Thompson AW, Chen JH, Caferro TR, Cummings ML, Deckhut CP, Adams ME, Tegley CM, Edwards JP, López FJ, Kallel EA, Karanewsky DS, Schrader WT, Marschke KB, Zhi L. Higuchi RI, et al. Among authors: kallel ea. Bioorg Med Chem Lett. 2007 Oct 1;17(19):5442-6. doi: 10.1016/j.bmcl.2007.07.034. Epub 2007 Jul 25. Bioorg Med Chem Lett. 2007. PMID: 17703938 Free PMC article.
Aza-retinoids as novel retinoid X receptor-specific agonists.
Farmer LJ, Marron KS, Canan Koch SS, Hwang CK, Kallel EA, Zhi L, Nadzan AM, Robertson DW, Bennani YL. Farmer LJ, et al. Among authors: kallel ea. Bioorg Med Chem Lett. 2006 May 1;16(9):2352-6. doi: 10.1016/j.bmcl.2005.12.003. Epub 2005 Dec 20. Bioorg Med Chem Lett. 2006. PMID: 16364638
Structure of the ligand-binding domain (LBD) of human androgen receptor in complex with a selective modulator LGD2226.
Wang F, Liu XQ, Li H, Liang KN, Miner JN, Hong M, Kallel EA, van Oeveren A, Zhi L, Jiang T. Wang F, et al. Among authors: kallel ea. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Nov 1;62(Pt 11):1067-71. doi: 10.1107/S1744309106039340. Epub 2006 Oct 25. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 17077481 Free PMC article.
Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors.
Plewe MB, Sokolova NV, Gantla VR, Brown ER, Naik S, Fetsko A, Lorimer DD, Dranow DM, Smutney H, Bullen J, Sidhu R, Master A, Wang J, Kallel EA, Zhang L, Kalveram B, Freiberg AN, Henkel G, McCormack K. Plewe MB, et al. Among authors: kallel ea. ACS Med Chem Lett. 2020 May 1;11(6):1160-1167. doi: 10.1021/acsmedchemlett.0c00025. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32550996 Free PMC article.
Conformational analysis of 2-substituted piperazines.
Kallel EA, Vangel C, Elbaum D. Kallel EA, et al. Bioorg Med Chem Lett. 2016 Jul 1;26(13):3010-3013. doi: 10.1016/j.bmcl.2016.05.022. Epub 2016 May 9. Bioorg Med Chem Lett. 2016. PMID: 27212066
Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery.
Ekins S, de Siqueira-Neto JL, McCall LI, Sarker M, Yadav M, Ponder EL, Kallel EA, Kellar D, Chen S, Arkin M, Bunin BA, McKerrow JH, Talcott C. Ekins S, et al. Among authors: kallel ea. PLoS Negl Trop Dis. 2015 Jun 26;9(6):e0003878. doi: 10.1371/journal.pntd.0003878. eCollection 2015. PLoS Negl Trop Dis. 2015. PMID: 26114876 Free PMC article.
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