Brown KA - Search Results

1

Molecules incorporating a benzothiazole core scaffold inhibit the N-myristoyltransferase of Plasmodium falciparum.

Bowyer PW, Gunaratne RS, Grainger M, Withers-Martinez C, Wickramsinghe SR, Tate EW, Leatherbarrow RJ, Brown KA, Holder AA, Smith DF. Bowyer PW, et al. Among authors: brown ka. Biochem J. 2007 Dec 1;408(2):173-80. doi: 10.1042/BJ20070692. Biochem J. 2007. PMID: 17714074 Free PMC article.

2

Characterization and selective inhibition of myristoyl-CoA:protein N-myristoyltransferase from Trypanosoma brucei and Leishmania major.

Panethymitaki C, Bowyer PW, Price HP, Leatherbarrow RJ, Brown KA, Smith DF. Panethymitaki C, et al. Among authors: brown ka. Biochem J. 2006 Jun 1;396(2):277-85. doi: 10.1042/BJ20051886. Biochem J. 2006. PMID: 16480339 Free PMC article.

3

N-myristoyltransferase: a prospective drug target for protozoan parasites.

Bowyer PW, Tate EW, Leatherbarrow RJ, Holder AA, Smith DF, Brown KA. Bowyer PW, et al. Among authors: brown ka. ChemMedChem. 2008 Mar;3(3):402-8. doi: 10.1002/cmdc.200700301. ChemMedChem. 2008. PMID: 18324715 Review. No abstract available.

4

Structural basis of molecular recognition of the Leishmania small hydrophilic endoplasmic reticulum-associated protein (SHERP) at membrane surfaces.

Moore B, Miles AJ, Guerra-Giraldez C, Simpson P, Iwata M, Wallace BA, Matthews SJ, Smith DF, Brown KA. Moore B, et al. Among authors: brown ka. J Biol Chem. 2011 Mar 18;286(11):9246-56. doi: 10.1074/jbc.M110.130427. Epub 2010 Nov 24. J Biol Chem. 2011. PMID: 21106528 Free PMC article.

5

Protein farnesyl and N-myristoyl transferases: piggy-back medicinal chemistry targets for the development of antitrypanosomatid and antimalarial therapeutics.

Gelb MH, Van Voorhis WC, Buckner FS, Yokoyama K, Eastman R, Carpenter EP, Panethymitaki C, Brown KA, Smith DF. Gelb MH, et al. Among authors: brown ka. Mol Biochem Parasitol. 2003 Feb;126(2):155-63. doi: 10.1016/s0166-6851(02)00282-7. Mol Biochem Parasitol. 2003. PMID: 12615314 Review.

6

The multidrug resistance efflux complex, EmrAB from Escherichia coli forms a dimer in vitro.

Tanabe M, Szakonyi G, Brown KA, Henderson PJ, Nield J, Byrne B. Tanabe M, et al. Among authors: brown ka. Biochem Biophys Res Commun. 2009 Mar 6;380(2):338-42. doi: 10.1016/j.bbrc.2009.01.081. Epub 2009 Jan 24. Biochem Biophys Res Commun. 2009. PMID: 19171121

7

Progress in the characterization of catalase-peroxidase from Mycobacterium tuberculosis.

Nagy JM, Cass AE, Brown KA. Nagy JM, et al. Among authors: brown ka. Biochem Soc Trans. 1995 May;23(2):152S. doi: 10.1042/bst023152s. Biochem Soc Trans. 1995. PMID: 7672183 No abstract available.

8

Structural characterization of recombinant catalase-peroxidase from Mycobacterium tuberculosis.

Nagy JM, Svergun D, Koch MH, Cass AE, Brown KA. Nagy JM, et al. Among authors: brown ka. Biochem Soc Trans. 1997 Nov;25(4):S617. doi: 10.1042/bst025s617. Biochem Soc Trans. 1997. PMID: 9450045 No abstract available.

9

Twists and turns: a tale of two shikimate-pathway enzymes.

Brown KA, Carpenter EP, Watson KA, Coggins JR, Hawkins AR, Koch MH, Svergun DI. Brown KA, et al. Biochem Soc Trans. 2003 Jun;31(Pt 3):543-7. doi: 10.1042/bst0310543. Biochem Soc Trans. 2003. PMID: 12773153 Review.

10

Expression of recombinant aroB-encoded dehydroquinate synthase from pathogenic microorganisms.

Skinner MA, Günel-Ozcan A, Shafiq M, Maskell DJ, Brown KA. Skinner MA, et al. Among authors: brown ka. Biochem Soc Trans. 1998 Aug;26(3):S280. doi: 10.1042/bst026s280. Biochem Soc Trans. 1998. PMID: 9765999 No abstract available.

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