Serrels B - Search Results

1

Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex.

Serrels B, Serrels A, Brunton VG, Holt M, McLean GW, Gray CH, Jones GE, Frame MC. Serrels B, et al. Among authors: serrels a. Nat Cell Biol. 2007 Sep;9(9):1046-56. doi: 10.1038/ncb1626. Epub 2007 Aug 26. Nat Cell Biol. 2007. PMID: 17721515

2

SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling.

Westhoff MA, Serrels B, Fincham VJ, Frame MC, Carragher NO. Westhoff MA, et al. Among authors: serrels b. Mol Cell Biol. 2004 Sep;24(18):8113-33. doi: 10.1128/MCB.24.18.8113-8133.2004. Mol Cell Biol. 2004. PMID: 15340073 Free PMC article.

3

Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression.

McLean GW, Komiyama NH, Serrels B, Asano H, Reynolds L, Conti F, Hodivala-Dilke K, Metzger D, Chambon P, Grant SG, Frame MC. McLean GW, et al. Among authors: serrels b. Genes Dev. 2004 Dec 15;18(24):2998-3003. doi: 10.1101/gad.316304. Genes Dev. 2004. PMID: 15601818 Free PMC article.

4

Identification of Src-specific phosphorylation site on focal adhesion kinase: dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior.

Brunton VG, Avizienyte E, Fincham VJ, Serrels B, Metcalf CA 3rd, Sawyer TK, Frame MC. Brunton VG, et al. Among authors: serrels b. Cancer Res. 2005 Feb 15;65(4):1335-42. doi: 10.1158/0008-5472.CAN-04-1949. Cancer Res. 2005. PMID: 15735019

5

A novel Src kinase inhibitor reduces tumour formation in a skin carcinogenesis model.

Serrels B, Serrels A, Mason SM, Baldeschi C, Ashton GH, Canel M, Mackintosh LJ, Doyle B, Green TP, Frame MC, Sansom OJ, Brunton VG. Serrels B, et al. Among authors: serrels a. Carcinogenesis. 2009 Feb;30(2):249-57. doi: 10.1093/carcin/bgn278. Epub 2008 Dec 5. Carcinogenesis. 2009. PMID: 19060248

6

A complex between FAK, RACK1, and PDE4D5 controls spreading initiation and cancer cell polarity.

Serrels B, Sandilands E, Serrels A, Baillie G, Houslay MD, Brunton VG, Canel M, Machesky LM, Anderson KI, Frame MC. Serrels B, et al. Among authors: serrels a. Curr Biol. 2010 Jun 22;20(12):1086-92. doi: 10.1016/j.cub.2010.04.042. Epub 2010 May 20. Curr Biol. 2010. PMID: 20493699 Free article.

7

The FERM domain: organizing the structure and function of FAK.

Frame MC, Patel H, Serrels B, Lietha D, Eck MJ. Frame MC, et al. Among authors: serrels b. Nat Rev Mol Cell Biol. 2010 Nov;11(11):802-14. doi: 10.1038/nrm2996. Nat Rev Mol Cell Biol. 2010. PMID: 20966971 Review.

8

Quantitative in vivo imaging of the effects of inhibiting integrin signaling via Src and FAK on cancer cell movement: effects on E-cadherin dynamics.

Canel M, Serrels A, Miller D, Timpson P, Serrels B, Frame MC, Brunton VG. Canel M, et al. Among authors: serrels b, serrels a. Cancer Res. 2010 Nov 15;70(22):9413-22. doi: 10.1158/0008-5472.CAN-10-1454. Epub 2010 Nov 2. Cancer Res. 2010. PMID: 21045155 Free PMC article.

9

Signaling of the direction-sensing FAK/RACK1/PDE4D5 complex to the small GTPase Rap1.

Serrels B, Sandilands E, Frame MC. Serrels B, et al. Small GTPases. 2011 Jan;2(1):54-61. doi: 10.4161/sgtp.2.1.15137. Small GTPases. 2011. PMID: 21686284 Free PMC article.

10

Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling.

Sandilands E, Serrels B, McEwan DG, Morton JP, Macagno JP, McLeod K, Stevens C, Brunton VG, Langdon WY, Vidal M, Sansom OJ, Dikic I, Wilkinson S, Frame MC. Sandilands E, et al. Among authors: serrels b. Nat Cell Biol. 2011 Dec 4;14(1):51-60. doi: 10.1038/ncb2386. Nat Cell Biol. 2011. PMID: 22138575

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