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Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation.
Orlovsky K, Kalinkovich A, Rozovskaia T, Shezen E, Itkin T, Alder H, Ozer HG, Carramusa L, Avigdor A, Volinia S, Buchberg A, Mazo A, Kollet O, Largman C, Croce CM, Nakamura T, Lapidot T, Canaani E. Orlovsky K, et al. Among authors: nakamura t. Proc Natl Acad Sci U S A. 2011 May 10;108(19):7956-61. doi: 10.1073/pnas.1103154108. Epub 2011 Apr 25. Proc Natl Acad Sci U S A. 2011. PMID: 21518888 Free PMC article.
Combined loss of function of two different loci of miR-15/16 drives the pathogenesis of acute myeloid leukemia.
Lovat F, Nigita G, Distefano R, Nakamura T, Gasparini P, Tomasello L, Fadda P, Ibrahimova N, Catricalà S, Palamarchuk A, Caligiuri MA, Gallì A, Malcovati L, Minden MD, Croce CM. Lovat F, et al. Among authors: nakamura t. Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):12332-12340. doi: 10.1073/pnas.2003597117. Epub 2020 May 18. Proc Natl Acad Sci U S A. 2020. PMID: 32424097 Free PMC article.
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia.
Garzon R, Volinia S, Liu CG, Fernandez-Cymering C, Palumbo T, Pichiorri F, Fabbri M, Coombes K, Alder H, Nakamura T, Flomenberg N, Marcucci G, Calin GA, Kornblau SM, Kantarjian H, Bloomfield CD, Andreeff M, Croce CM. Garzon R, et al. Among authors: nakamura t. Blood. 2008 Mar 15;111(6):3183-9. doi: 10.1182/blood-2007-07-098749. Epub 2008 Jan 10. Blood. 2008. PMID: 18187662 Free PMC article.
Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia.
Fabbri M, Bottoni A, Shimizu M, Spizzo R, Nicoloso MS, Rossi S, Barbarotto E, Cimmino A, Adair B, Wojcik SE, Valeri N, Calore F, Sampath D, Fanini F, Vannini I, Musuraca G, Dell'Aquila M, Alder H, Davuluri RV, Rassenti LZ, Negrini M, Nakamura T, Amadori D, Kay NE, Rai KR, Keating MJ, Kipps TJ, Calin GA, Croce CM. Fabbri M, et al. Among authors: nakamura t. JAMA. 2011 Jan 5;305(1):59-67. doi: 10.1001/jama.2010.1919. JAMA. 2011. PMID: 21205967 Free PMC article.
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