Lew R - Search Results

1

Beta-amino acid-containing hybrid peptides--new opportunities in peptidomimetics.

Aguilar MI, Purcell AW, Devi R, Lew R, Rossjohn J, Smith AI, Perlmutter P. Aguilar MI, et al. Among authors: lew r. Org Biomol Chem. 2007 Sep 21;5(18):2884-90. doi: 10.1039/b708507a. Epub 2007 Aug 3. Org Biomol Chem. 2007. PMID: 17728852

2

Inhibitors of metalloendopeptidase EC 3.4.24.15 and EC 3.4.24.16 stabilized against proteolysis by the incorporation of beta-amino acids.

Steer D, Lew R, Perlmutter P, Smith AI, Aguilar MI. Steer D, et al. Among authors: lew r. Biochemistry. 2002 Sep 3;41(35):10819-26. doi: 10.1021/bi0203334. Biochemistry. 2002. PMID: 12196021

3

Beta-amino acids: versatile peptidomimetics.

Steer DL, Lew RA, Perlmutter P, Smith AI, Aguilar MI. Steer DL, et al. Curr Med Chem. 2002 Apr;9(8):811-22. doi: 10.2174/0929867024606759. Curr Med Chem. 2002. PMID: 11966446 Review.

4

β-Amino acid substitution to investigate the recognition of angiotensin II (AngII) by angiotensin converting enzyme 2 (ACE2).

Clayton D, Hanchapola I, Hausler N, Unabia S, Lew RA, Widdop RE, Smith AI, Perlmutter P, Aguilar MI. Clayton D, et al. J Mol Recognit. 2011 Mar-Apr;24(2):235-44. doi: 10.1002/jmr.1041. J Mol Recognit. 2011. PMID: 20549604

5

Bradykinin analogues with beta-amino acid substitutions reveal subtle differences in substrate specificity between the endopeptidases EC 3.4.24.15 and EC 3.4.24.16.

Lew RA, Boulos E, Stewart KM, Perlmutter P, Harte MF, Bond S, Aguilar MI, Smith AI. Lew RA, et al. J Pept Sci. 2000 Sep;6(9):440-5. doi: 10.1002/1099-1387(200009)6:9<440::AID-PSC280>3.0.CO;2-K. J Pept Sci. 2000. PMID: 11016880

6

Design and synthesis of inhibitors incorporating beta -amino acids of metalloendopeptidase EC 3.4.24.15.

Steer DL, Lew RA, Perlmutter P, Smith AI, Aguilar MI. Steer DL, et al. Among authors: lew ra. J Pept Sci. 2000 Sep;6(9):470-7. doi: 10.1002/1099-1387(200009)6:9<470::AID-PSC287>3.0.CO;2-X. J Pept Sci. 2000. PMID: 11016884

7

Quenched fluorescent substrate-based peptidase assays.

Lew RA, Tochon-Danguy N, Hamilton CA, Stewart KM, Aguilar MI, Smith AI. Lew RA, et al. Methods Mol Biol. 2005;298:143-50. doi: 10.1385/1-59259-877-3:143. Methods Mol Biol. 2005. PMID: 16044545

8

Substrate analogs incorporating beta-amino acids: potential application for peptidase inhibition.

Lew RA, Boulos E, Stewart KM, Perlmutter P, Harte MF, Bond S, Reeve SB, Norman MU, Lew MJ, Aguilar MI, Smith AI. Lew RA, et al. Among authors: lew mj. FASEB J. 2001 Jul;15(9):1664-6. doi: 10.1096/fj.00-0805fje. FASEB J. 2001. PMID: 11427520 No abstract available.

9

Identification and characterization of an amidating enzyme in ovine heart.

Lew RA, Smith AI. Lew RA, et al. Clin Exp Pharmacol Physiol. 1993 Apr;20(4):231-8. doi: 10.1111/j.1440-1681.1993.tb01675.x. Clin Exp Pharmacol Physiol. 1993. PMID: 8485923

10

Soluble metalloendopeptidases and neuroendocrine signaling.

Shrimpton CN, Smith AI, Lew RA. Shrimpton CN, et al. Endocr Rev. 2002 Oct;23(5):647-64. doi: 10.1210/er.2001-0032. Endocr Rev. 2002. PMID: 12372844 Review.

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