Göbel M - Search Results

1

Fluorescence correlation spectroscopy at single molecule level on the Tat-TAR complex and its inhibitors.

Nandi CK, Parui PP, Brutschy B, Scheffer U, Göbel M. Nandi CK, et al. Among authors: gobel m. Biopolymers. 2008 Jan;89(1):17-25. doi: 10.1002/bip.20835. Biopolymers. 2008. PMID: 17764074

2

Tripeptides from synthetic amino acids block the Tat-TAR association and slow down HIV spread in cell cultures.

Ludwig V, Krebs A, Stoll M, Dietrich U, Ferner J, Schwalbe H, Scheffer U, Dürner G, Göbel MW. Ludwig V, et al. Among authors: gobel mw. Chembiochem. 2007 Oct 15;8(15):1850-6. doi: 10.1002/cbic.200700232. Chembiochem. 2007. PMID: 17886825

3

Fragment based search for small molecule inhibitors of HIV-1 Tat-TAR.

Zeiger M, Stark S, Kalden E, Ackermann B, Ferner J, Scheffer U, Shoja-Bazargani F, Erdel V, Schwalbe H, Göbel MW. Zeiger M, et al. Among authors: gobel mw. Bioorg Med Chem Lett. 2014 Dec 15;24(24):5576-5580. doi: 10.1016/j.bmcl.2014.11.004. Epub 2014 Nov 6. Bioorg Med Chem Lett. 2014. PMID: 25466178

4

New inhibitors of the Tat-TAR RNA interaction found with a "fuzzy" pharmacophore model.

Renner S, Ludwig V, Boden O, Scheffer U, Göbel M, Schneider G. Renner S, et al. Among authors: gobel m. Chembiochem. 2005 Jun;6(6):1119-25. doi: 10.1002/cbic.200400376. Chembiochem. 2005. PMID: 15883975

5

Binding sites of the viral RNA element TAR and of TAR mutants for various peptide ligands, probed with LILBID: a new laser mass spectrometry.

Morgner N, Barth HD, Brutschy B, Scheffer U, Breitung S, Göbel M. Morgner N, et al. Among authors: gobel m. J Am Soc Mass Spectrom. 2008 Nov;19(11):1600-11. doi: 10.1016/j.jasms.2008.07.001. Epub 2008 Jul 3. J Am Soc Mass Spectrom. 2008. PMID: 18693035 Free article.

6

The concept of template-based de novo design from drug-derived molecular fragments and its application to TAR RNA.

Schüller A, Suhartono M, Fechner U, Tanrikulu Y, Breitung S, Scheffer U, Göbel MW, Schneider G. Schüller A, et al. Among authors: gobel mw. J Comput Aided Mol Des. 2008 Feb;22(2):59-68. doi: 10.1007/s10822-007-9157-4. Epub 2007 Dec 7. J Comput Aided Mol Des. 2008. PMID: 18064402

7

Fluorescence-based on-line detection as an analytical tool in RNA electrophoresis.

Scheffer U, Göbel M. Scheffer U, et al. Among authors: gobel m. Methods Mol Biol. 2005;288:261-72. doi: 10.1385/1-59259-823-4:261. Methods Mol Biol. 2005. PMID: 15333909

8

Scaffold hopping by "fuzzy" pharmacophores and its application to RNA targets.

Tanrikulu Y, Nietert M, Scheffer U, Proschak E, Grabowski K, Schneider P, Weidlich M, Karas M, Göbel M, Schneider G. Tanrikulu Y, et al. Among authors: gobel m. Chembiochem. 2007 Nov 5;8(16):1932-6. doi: 10.1002/cbic.200700195. Chembiochem. 2007. PMID: 17896338 No abstract available.

9

Metal-free catalysts for the hydrolysis of RNA derived from guanidines, 2-aminopyridines, and 2-aminobenzimidazoles.

Scheffer U, Strick A, Ludwig V, Peter S, Kalden E, Göbel MW. Scheffer U, et al. J Am Chem Soc. 2005 Feb 23;127(7):2211-7. doi: 10.1021/ja0443934. J Am Chem Soc. 2005. PMID: 15713099

10

A Cytidine Phosphoramidite with Protected Nitroxide Spin Label: Synthesis of a Full-Length TAR RNA and Investigation by In-Line Probing and EPR Spectroscopy.

Weinrich T, Jaumann EA, Scheffer U, Prisner TF, Göbel MW. Weinrich T, et al. Chemistry. 2018 Apr 20;24(23):6202-6207. doi: 10.1002/chem.201800167. Epub 2018 Apr 6. Chemistry. 2018. PMID: 29485736

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