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Structure-activity relationship study of novel NR2B-selective antagonists with arylamides to avoid reactive metabolites formation.
Kawai M, Sakurada I, Morita A, Iwamuro Y, Ando K, Omura H, Sakakibara S, Masuda T, Koike H, Honma T, Hattori K, Takashima T, Mizuno K, Mizutani M, Kawamura M. Kawai M, et al. Among authors: morita a. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5537-42. doi: 10.1016/j.bmcl.2007.08.033. Epub 2007 Aug 19. Bioorg Med Chem Lett. 2007. PMID: 17766107
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: design, synthesis, and structure-activity relationships.
Hayashi S, Nakata E, Morita A, Mizuno K, Yamamura K, Kato A, Ohashi K. Hayashi S, et al. Among authors: morita a. Bioorg Med Chem. 2010 Nov 1;18(21):7675-99. doi: 10.1016/j.bmc.2010.07.034. Epub 2010 Jul 21. Bioorg Med Chem. 2010. PMID: 20875743
Blood DNA virome associates with autoimmune diseases and COVID-19.
Sasa N, Kojima S, Koide R, Hasegawa T, Namkoong H, Hirota T, Watanabe R, Nakamura Y, Oguro-Igashira E, Ogawa K, Yata T, Sonehara K, Yamamoto K, Kishikawa T, Sakaue S, Edahiro R, Shirai Y, Maeda Y, Nii T, Chubachi S, Tanaka H, Yabukami H, Suzuki A, Nakajima K, Arase N, Okamoto T, Nishikawa R, Namba S, Naito T, Miyagawa I, Tanaka H, Ueno M, Ishitsuka Y, Furuta J, Kunimoto K, Kajihara I, Fukushima S, Miyachi H, Matsue H, Kamata M, Momose M, Bito T, Nagai H, Ikeda T, Horikawa T, Adachi A, Matsubara T, Ikumi K, Nishida E, Nakagawa I, Yagita-Sakamaki M, Yoshimura M, Ohshima S, Kinoshita M, Ito S, Arai T, Hirose M, Tanino Y, Nikaido T, Ichiwata T, Ohkouchi S, Hirano T, Takada T, Tazawa R, Morimoto K, Takaki M, Konno S, Suzuki M, Tomii K, Nakagawa A, Handa T, Tanizawa K, Ishii H, Ishida M, Kato T, Takeda N, Yokomura K, Matsui T, Uchida A, Inoue H, Imaizumi K, Goto Y, Kida H, Fujisawa T, Suda T, Yamada T, Satake Y, Ibata H, Saigusa M, Shirai T, Hizawa N, Nakata K; Japan COVID-19 Task Force; Imafuku S, Tada Y, Asano Y, Sato S, Nishigori C, Jinnin M, Ihn H, Asahina A, Saeki H, Kawamura T, Shimada S, Katayama I, Poisner HM, Mack TM, Bick AG, Higasa K, Okuno T, Mochizuki H, Ishii M, Koike R, K… See abstract for full author list ➔ Sasa N, et al. Among authors: morita a. Nat Genet. 2025 Jan;57(1):65-79. doi: 10.1038/s41588-024-02022-z. Epub 2025 Jan 3. Nat Genet. 2025. PMID: 39753770 Free PMC article.
The relationship between long COVID, labor productivity, and socioeconomic losses in Japan: A cohort study.
Konishi S, Masaki K, Shimamoto K, Ibuka Y, Goto R, Namkoong H, Chubachi S, Terai H, Asakura T, Miyata J, Azekawa S, Nakagawara K, Tanaka H, Morita A, Harada N, Sasano H, Nakamura A, Kusaka Y, Ohba T, Nakano Y, Nishio K, Nakajima Y, Suzuki S, Yoshida S, Tateno H, Fukunaga K. Konishi S, et al. Among authors: morita a. IJID Reg. 2024 Nov 20;14:100495. doi: 10.1016/j.ijregi.2024.100495. eCollection 2025 Mar. IJID Reg. 2024. PMID: 39717862 Free PMC article.
1,643 results