Carman CV - Search Results

1

Aberrant activation of integrin alpha4beta7 suppresses lymphocyte migration to the gut.

Park EJ, Mora JR, Carman CV, Chen J, Sasaki Y, Cheng G, von Andrian UH, Shimaoka M. Park EJ, et al. Among authors: carman cv. J Clin Invest. 2007 Sep;117(9):2526-38. doi: 10.1172/JCI31570. J Clin Invest. 2007. PMID: 17786243 Free PMC article.

2

Activation-induced conformational changes in the I domain region of lymphocyte function-associated antigen 1.

Ma Q, Shimaoka M, Lu C, Jing H, Carman CV, Springer TA. Ma Q, et al. Among authors: carman cv. J Biol Chem. 2002 Mar 22;277(12):10638-41. doi: 10.1074/jbc.M112417200. Epub 2002 Jan 15. J Biol Chem. 2002. PMID: 11792712 Free article.

3

Transition from rolling to firm adhesion is regulated by the conformation of the I domain of the integrin lymphocyte function-associated antigen-1.

Salas A, Shimaoka M, Chen S, Carman CV, Springer T. Salas A, et al. Among authors: carman cv. J Biol Chem. 2002 Dec 27;277(52):50255-62. doi: 10.1074/jbc.M209822200. Epub 2002 Oct 3. J Biol Chem. 2002. PMID: 12368274 Free article.

4

Directed evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity.

Jin M, Song G, Carman CV, Kim YS, Astrof NS, Shimaoka M, Wittrup DK, Springer TA. Jin M, et al. Among authors: carman cv. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5758-63. doi: 10.1073/pnas.0601164103. Epub 2006 Apr 4. Proc Natl Acad Sci U S A. 2006. PMID: 16595626 Free PMC article.

5

Regulation of outside-in signaling and affinity by the beta2 I domain of integrin alphaLbeta2.

Chen J, Yang W, Kim M, Carman CV, Springer TA. Chen J, et al. Among authors: carman cv. Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13062-7. doi: 10.1073/pnas.0605666103. Epub 2006 Aug 18. Proc Natl Acad Sci U S A. 2006. PMID: 16920795 Free PMC article.

6

A small molecule agonist of an integrin, alphaLbeta2.

Yang W, Carman CV, Kim M, Salas A, Shimaoka M, Springer TA. Yang W, et al. Among authors: carman cv. J Biol Chem. 2006 Dec 8;281(49):37904-12. doi: 10.1074/jbc.M606888200. Epub 2006 Oct 5. J Biol Chem. 2006. PMID: 17023419 Free PMC article.

7

Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1.

Peer D, Zhu P, Carman CV, Lieberman J, Shimaoka M. Peer D, et al. Among authors: carman cv. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4095-100. doi: 10.1073/pnas.0608491104. Epub 2007 Feb 28. Proc Natl Acad Sci U S A. 2007. PMID: 17360483 Free PMC article.

8

Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling.

Zhu J, Carman CV, Kim M, Shimaoka M, Springer TA, Luo BH. Zhu J, et al. Among authors: carman cv. Blood. 2007 Oct 1;110(7):2475-83. doi: 10.1182/blood-2007-03-080077. Epub 2007 Jul 5. Blood. 2007. PMID: 17615290 Free PMC article.

9

Genetic perturbation of the putative cytoplasmic membrane-proximal salt bridge aberrantly activates alpha(4) integrins.

Imai Y, Park EJ, Peer D, Peixoto A, Cheng G, von Andrian UH, Carman CV, Shimaoka M. Imai Y, et al. Among authors: carman cv. Blood. 2008 Dec 15;112(13):5007-15. doi: 10.1182/blood-2008-03-144543. Epub 2008 Sep 22. Blood. 2008. PMID: 18809756 Free PMC article.

10

Distinct roles for LFA-1 affinity regulation during T-cell adhesion, diapedesis, and interstitial migration in lymph nodes.

Park EJ, Peixoto A, Imai Y, Goodarzi A, Cheng G, Carman CV, von Andrian UH, Shimaoka M. Park EJ, et al. Among authors: carman cv. Blood. 2010 Feb 25;115(8):1572-81. doi: 10.1182/blood-2009-08-237917. Epub 2009 Dec 18. Blood. 2010. PMID: 20023213 Free PMC article.

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