Shimaoka M - Search Results

1

Aberrant activation of integrin alpha4beta7 suppresses lymphocyte migration to the gut.

Park EJ, Mora JR, Carman CV, Chen J, Sasaki Y, Cheng G, von Andrian UH, Shimaoka M. Park EJ, et al. Among authors: shimaoka m. J Clin Invest. 2007 Sep;117(9):2526-38. doi: 10.1172/JCI31570. J Clin Invest. 2007. PMID: 17786243 Free PMC article.

2

Activation-induced conformational changes in the I domain region of lymphocyte function-associated antigen 1.

Ma Q, Shimaoka M, Lu C, Jing H, Carman CV, Springer TA. Ma Q, et al. Among authors: shimaoka m. J Biol Chem. 2002 Mar 22;277(12):10638-41. doi: 10.1074/jbc.M112417200. Epub 2002 Jan 15. J Biol Chem. 2002. PMID: 11792712 Free article.

3

Transition from rolling to firm adhesion is regulated by the conformation of the I domain of the integrin lymphocyte function-associated antigen-1.

Salas A, Shimaoka M, Chen S, Carman CV, Springer T. Salas A, et al. Among authors: shimaoka m. J Biol Chem. 2002 Dec 27;277(52):50255-62. doi: 10.1074/jbc.M209822200. Epub 2002 Oct 3. J Biol Chem. 2002. PMID: 12368274 Free article.

4

Activation of integrin beta-subunit I-like domains by one-turn C-terminal alpha-helix deletions.

Yang W, Shimaoka M, Chen J, Springer TA. Yang W, et al. Among authors: shimaoka m. Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2333-8. doi: 10.1073/pnas.0307291101. Proc Natl Acad Sci U S A. 2004. PMID: 14983010 Free PMC article.

5

Rolling adhesion through an extended conformation of integrin alphaLbeta2 and relation to alpha I and beta I-like domain interaction.

Salas A, Shimaoka M, Kogan AN, Harwood C, von Andrian UH, Springer TA. Salas A, et al. Among authors: shimaoka m. Immunity. 2004 Apr;20(4):393-406. doi: 10.1016/s1074-7613(04)00082-2. Immunity. 2004. PMID: 15084269 Free article.

6

Directed evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity.

Jin M, Song G, Carman CV, Kim YS, Astrof NS, Shimaoka M, Wittrup DK, Springer TA. Jin M, et al. Among authors: shimaoka m. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5758-63. doi: 10.1073/pnas.0601164103. Epub 2006 Apr 4. Proc Natl Acad Sci U S A. 2006. PMID: 16595626 Free PMC article.

7

A small molecule agonist of an integrin, alphaLbeta2.

Yang W, Carman CV, Kim M, Salas A, Shimaoka M, Springer TA. Yang W, et al. Among authors: shimaoka m. J Biol Chem. 2006 Dec 8;281(49):37904-12. doi: 10.1074/jbc.M606888200. Epub 2006 Oct 5. J Biol Chem. 2006. PMID: 17023419 Free PMC article.

8

Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1.

Peer D, Zhu P, Carman CV, Lieberman J, Shimaoka M. Peer D, et al. Among authors: shimaoka m. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4095-100. doi: 10.1073/pnas.0608491104. Epub 2007 Feb 28. Proc Natl Acad Sci U S A. 2007. PMID: 17360483 Free PMC article.

9

Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling.

Zhu J, Carman CV, Kim M, Shimaoka M, Springer TA, Luo BH. Zhu J, et al. Among authors: shimaoka m. Blood. 2007 Oct 1;110(7):2475-83. doi: 10.1182/blood-2007-03-080077. Epub 2007 Jul 5. Blood. 2007. PMID: 17615290 Free PMC article.

10

Genetic perturbation of the putative cytoplasmic membrane-proximal salt bridge aberrantly activates alpha(4) integrins.

Imai Y, Park EJ, Peer D, Peixoto A, Cheng G, von Andrian UH, Carman CV, Shimaoka M. Imai Y, et al. Among authors: shimaoka m. Blood. 2008 Dec 15;112(13):5007-15. doi: 10.1182/blood-2008-03-144543. Epub 2008 Sep 22. Blood. 2008. PMID: 18809756 Free PMC article.

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