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Page 1
Synthesis of a [2-pyridinyl-18F]-labelled fluoro derivative of (-)-cytisine as a candidate radioligand for brain nicotinic alpha4beta2 receptor imaging with PET.
Roger G, Lagnel B, Rouden J, Besret L, Valette H, Demphel S, Gopisetti J, Coulon C, Ottaviani M, Wrenn LA, Letchworth SR, Bohme GA, Benavides J, Lasne MC, Bottlaender M, Dollé F. Roger G, et al. Among authors: demphel s. Bioorg Med Chem. 2003 Dec 1;11(24):5333-43. doi: 10.1016/j.bmc.2003.09.042. Bioorg Med Chem. 2003. PMID: 14642577
Synthesis, radiosynthesis and in vivo preliminary evaluation of [11C]LBT-999, a selective radioligand for the visualisation of the dopamine transporter with PET.
Dollé F, Emond P, Mavel S, Demphel S, Hinnen F, Mincheva Z, Saba W, Valette H, Chalon S, Halldin C, Helfenbein J, Legaillard J, Madelmont JC, Deloye JB, Bottlaender M, Guilloteau D. Dollé F, et al. Among authors: demphel s. Bioorg Med Chem. 2006 Feb 15;14(4):1115-25. doi: 10.1016/j.bmc.2005.09.035. Epub 2005 Oct 10. Bioorg Med Chem. 2006. PMID: 16219467
[18F]DPA-714, [18F]PBR111 and [18F]FEDAA1106-selective radioligands for imaging TSPO 18 kDa with PET: automated radiosynthesis on a TRACERLAb FX-FN synthesizer and quality controls.
Kuhnast B, Damont A, Hinnen F, Catarina T, Demphel S, Le Helleix S, Coulon C, Goutal S, Gervais P, Dollé F. Kuhnast B, et al. Among authors: demphel s. Appl Radiat Isot. 2012 Mar;70(3):489-97. doi: 10.1016/j.apradiso.2011.10.015. Epub 2011 Nov 11. Appl Radiat Isot. 2012. PMID: 22104496
Translational Preclinical PET Imaging and Metabolic Evaluation of a New Cannabinoid 2 Receptor (CB2R) Radioligand, (Z)-N-(3-(2-(2-[18F]Fluoroethoxy)ethyl)-4,5-dimethylthiazol-2(3H)-ylidene)-2,2,3,3-tetramethylcyclopropane-1-carboxamide.
Auvity S, Attili B, Caillé F, Goislard M, Cayla J, Hinnen F, Demphel S, Brulon V, Bottlaender M, Leroy C, Bormans G, Kuhnast B, Peyronneau MA. Auvity S, et al. Among authors: demphel s. ACS Pharmacol Transl Sci. 2024 Sep 13;7(10):3144-3154. doi: 10.1021/acsptsci.4c00348. eCollection 2024 Oct 11. ACS Pharmacol Transl Sci. 2024. PMID: 39421654
Synthesis of novel halo and tosyloxy nortropane derivatives as efficient precursors for the one-step synthesis of the dopamine transporter PET ligand [(18)F]FECNT.
Pijarowska-Kruszyna J, Jaron AW, Kachniarz A, Kasprzak K, Kowalska A, Malkowski B, Demphel S, Dollé F, Mikolajczak R. Pijarowska-Kruszyna J, et al. Among authors: demphel s. J Labelled Comp Radiopharm. 2014 Mar;57(3):148-57. doi: 10.1002/jlcr.3181. Epub 2014 Feb 5. J Labelled Comp Radiopharm. 2014. PMID: 24497079