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(1R,2S)-4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production.
Hu LY, Du D, Hoffman J, Smith Y, Fedij V, Kostlan C, Johnson TR, Huang Y, Kesten S, Harter W, Yue WS, Li JJ, Barvian N, Mitchell L, Lei HJ, Lefker B, Carroll M, Dettling D, Krieger-Burke T, Samas B, Yalamanchili R, Lapham K, Pocalyko D, Sliskovic D, Ciotti S, Stoller B, Hena MA, Ding Q, Maiti SN, Stier M, Welgus H. Hu LY, et al. Among authors: ding q. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5983-8. doi: 10.1016/j.bmcl.2007.07.075. Epub 2007 Aug 21. Bioorg Med Chem Lett. 2007. PMID: 17827000
Synthesis and SAR of novel conformationally-restricted oxazolidinones possessing gram-positive and fastidious gram-negative antibacterial activity. Part 1: Substituted pyrazoles.
Boyer FE, Vara Prasad JV, Choy AL, Chupak L, Dermyer MR, Ding Q, Huband MD, Jiao W, Kaneko T, Khlebnikov V, Kim JY, Lall MS, Maiti SN, Romero K, Wu X. Boyer FE, et al. Among authors: ding q. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4694-8. doi: 10.1016/j.bmcl.2007.05.056. Epub 2007 May 24. Bioorg Med Chem Lett. 2007. PMID: 17590334
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