Ling H - Search Results

1

A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment.

Bauer J, Xing G, Yagi H, Sayer JM, Jerina DM, Ling H. Bauer J, et al. Among authors: ling h. Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):14905-10. doi: 10.1073/pnas.0700717104. Epub 2007 Sep 11. Proc Natl Acad Sci U S A. 2007. PMID: 17848527 Free PMC article.

2

Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase.

Ling H, Sayer JM, Plosky BS, Yagi H, Boudsocq F, Woodgate R, Jerina DM, Yang W. Ling H, et al. Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2265-9. doi: 10.1073/pnas.0308332100. Proc Natl Acad Sci U S A. 2004. PMID: 14982998 Free PMC article.

3

Structure and mechanism of error-free replication past the major benzo[a]pyrene adduct by human DNA polymerase κ.

Jha V, Bian C, Xing G, Ling H. Jha V, et al. Among authors: ling h. Nucleic Acids Res. 2016 Jun 2;44(10):4957-67. doi: 10.1093/nar/gkw204. Epub 2016 Mar 31. Nucleic Acids Res. 2016. PMID: 27034468 Free PMC article.

4

Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA.

Xing G, Kirouac K, Shin YJ, Bell SD, Ling H. Xing G, et al. Among authors: ling h. Mol Microbiol. 2009 Feb;71(3):678-91. doi: 10.1111/j.1365-2958.2008.06553.x. Epub 2008 Dec 1. Mol Microbiol. 2009. PMID: 19054331 Free article.

5

Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.

Hlinkova V, Xing G, Bauer J, Shin YJ, Dionne I, Rajashankar KR, Bell SD, Ling H. Hlinkova V, et al. Among authors: ling h. Acta Crystallogr D Biol Crystallogr. 2008 Sep;64(Pt 9):941-9. doi: 10.1107/S0907444908021665. Epub 2008 Aug 13. Acta Crystallogr D Biol Crystallogr. 2008. PMID: 18703842 Free PMC article.

6

Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota.

Kirouac KN, Ling H. Kirouac KN, et al. Among authors: ling h. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3210-5. doi: 10.1073/pnas.1013909108. Epub 2011 Feb 7. Proc Natl Acad Sci U S A. 2011. PMID: 21300901 Free PMC article.

7

Structural basis of accurate replication beyond a bulky major benzo[a]pyrene adduct by human DNA polymerase kappa.

Jha V, Ling H. Jha V, et al. Among authors: ling h. DNA Repair (Amst). 2017 Jan;49:43-50. doi: 10.1016/j.dnarep.2016.11.001. Epub 2016 Nov 19. DNA Repair (Amst). 2017. PMID: 27894903

8

Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4.

Wong JH, Brown JA, Suo Z, Blum P, Nohmi T, Ling H. Wong JH, et al. Among authors: ling h. EMBO J. 2010 Jun 16;29(12):2059-69. doi: 10.1038/emboj.2010.101. Epub 2010 May 28. EMBO J. 2010. PMID: 20512114 Free PMC article.

9

Snapshots of a Y-family DNA polymerase in replication: substrate-induced conformational transitions and implications for fidelity of Dpo4.

Wong JH, Fiala KA, Suo Z, Ling H. Wong JH, et al. Among authors: ling h. J Mol Biol. 2008 May 30;379(2):317-30. doi: 10.1016/j.jmb.2008.03.038. Epub 2008 Mar 28. J Mol Biol. 2008. PMID: 18448122

10

Structural mechanism of replication stalling on a bulky amino-polycyclic aromatic hydrocarbon DNA adduct by a y family DNA polymerase.

Kirouac KN, Basu AK, Ling H. Kirouac KN, et al. Among authors: ling h. J Mol Biol. 2013 Nov 15;425(22):4167-76. doi: 10.1016/j.jmb.2013.07.020. Epub 2013 Jul 20. J Mol Biol. 2013. PMID: 23876706 Free PMC article.

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